Fatty Acid Metabolism Flashcards
(9 cards)
1
Q
Where does beta-oxidation occur?
A
In the mitochondrial matrix
2
Q
What is a brief description of beta-oxidation?
A
Activation via CoA, then removal of 2-carbon units at a time to form acetyl-CoA.
3
Q
Each cycle of beta oxidation produces:
A
1 NADH
1 FADH2
1 acetyl-CoA
4
Q
Why does beta-oxidation produce more energy than glycolysis?
A
Fatty acids are much more reduced and produce much more acetyl-CoA, NADH, and FADH2, leading to more ATP synthesized.
5
Q
How many steps does beta oxidation consist of?
A
4
6
Q
What does step 1 do?
A
Oxidation of the FA introduces a double bond. FAD is reduced.
7
Q
What does step 2 do?
A
Hydration of the double bond.
8
Q
What does step 3 do?
A
Oxidation to form a keto group. NAD+ is reduced.
9
Q
What does step 4 do?
A
CoA attacks the keto group and acetyl-CoA falls off.
