Replication Flashcards
(10 cards)
How are the leading and lagging strand produced differently?
The leading strand is synthesized continuously while the lagging strand is synthesized in the opposite direction in short fragments.
What are Okazaki fragments?
Nucleotide segments that form the lagging strand.
In which direction is the leading strand synthesized?
5’ to 3’
What are the steps of replication?
Initiation
Translation & Elongation
Termination
What enzyme is responsible for opening up DNA for initiation?
Helicase
Which enzyme relieves tension on the DNA strand from twisting?
Topoisomerase
Which enzyme conducts the replication synthesis?
DNA polymerase
Which enzyme joins fragments together?
DNA ligase
When does termination occur?
When replication forks meet
Three types of mutation?
substitution
insertion
deletion