Feline Immunodeficiency Virus Flashcards Preview

Small Animal Medicine > Feline Immunodeficiency Virus > Flashcards

Flashcards in Feline Immunodeficiency Virus Deck (14)
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1
Q

FIV is spread predominantly by

A

biting

2
Q

FIV is present in

A

saliva, blood, body fluids

3
Q

is in-utero FIV infection possible?

A

yes

4
Q

FIV is most common in

A

male, free roaming cats

5
Q

Do cats recover from FIV infection?

A

No. All persistently infected.

6
Q

Main cellular target of FIV

A

CD4+

[+many others - complex effects on the immune system]

7
Q

Pathogenesis of FIV

A
  • inoculation (usually via bite wound)
  • initial viraemia. Subsides after 3-6mo
    …usually years…
  • depletion of T & B cells
  • immunodeficiency
8
Q

The two outcomes of FIV infection

A
  1. Terminal phase: death fromopportunistic infections, neoplastic or neurologic disease or myelosuppression, immune mediated disease.
  2. death from other causes without entering terminal phase
9
Q

CSs FIV infection

A

non-specific. Weight loss, lethargy, inappetance, lymphadenopathy, gingivitis/stomatitis, pyrexia, chronic URT signs or chronic diarrhoea or skin disease.

10
Q

Testing for FIV

A

for antibodies against p24 or p120

Should confirm with immunofluorescence, WB or PCR

11
Q

Issue with testing

A

10-15% infected cats have no detectable antibodies

  • early in infection
  • immune collapse
  • failure of test kit
12
Q

May get -ve AB test in advanced FIP due to

A

Immune collapse

13
Q

Management of FIV +ve animals

A
  • house inside + neuter
  • avoid raw food and hunting
  • inactivated vaccine ONLY if in contact with other cats.
14
Q

Does the FIV vaccine cause a +ve test result?

A

Yes - general test used is for AB.