Female Repro Flashcards

(54 cards)

1
Q

the female reproductive tract consists of 5 things

A
ovaries
oviduct
uterus
cervix
vagina
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2
Q

the ovaries are responsible for

A

the development of gametes and synthesis and secretion of hormones

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3
Q

the oviduct is responsible for

A

the transport fo the oocyte + associated cells from ovary to uterus

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4
Q

uterus consits of what 2 things

A

myometrium and enodmetrium

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5
Q

the uterus does what ?

A

provides the appropriate environment for the development of the fertilized egg

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6
Q

the cervix provides a

A

strong, collagenous boundary between the uterus and vagina

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7
Q

the vagina is known as the

A

birth canal

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8
Q

the female gamete is known as the

A

oocyte

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9
Q

when do oocytes first start to develop?

A

prior to birth

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10
Q

two major types of estrogen

A

17 beta estradiol

estrone

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11
Q

another major hormoen from the ovary is

A

progesterone

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12
Q

where is progesterone mainly produced?

A

the corpus luteum

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13
Q

the ovaries produce 2 peptide hormones

A

inhibin

relaxin

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14
Q

inhibin is produced by what cell type?

A

granulosa cells

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15
Q

the development of a follicle from the primordial state to pre-ovulatory stage takes how long?

A

14 days

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16
Q

how long does ovulation take?

A

about 1 day

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17
Q

the corpus luteum functions for about how long?

A

14 days

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18
Q

FSH acts in what cells? and cause secretion of what?

A

granulosa cells and cause secretion of estradiol

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19
Q

FSH and estradiol causes granulosa cells to what?

A

proliferate

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20
Q

granulosa cells need what 4 things to actually proliferate?

A

FSH, estradiol LH and theca cells

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21
Q

why is LH and theca cells needed for granulosa cells?

A

they create the precursers for estradiol synthesis

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22
Q

the signal for ovulation is what?

A

large increase in LH secretion

23
Q

what receptor is necessary for ovulation

24
Q

the formation of the corpus luteum is initiated by what

25
estrogens stimulates growth of the
endometrium
26
estrogen acts on the myometrium to increase 3 things
contractile proteins, muscular activity and the number of gap junctions
27
progesterone inhibits the _____ of the uterus
contractility
28
when the corpus luteum degenerates what else happens?
the endometrium degenerates and is sloughed
29
within mammary glands, estrogen promotes 3 things
duct development, stromal proliferation and fat deposition
30
within mammary glands, progesterone is necessary for
lobuloalveolar development
31
many tumors, when estrogen is removed
stop growing
32
progesterone has a ______ effect
thermogenic effect
33
progesterone in combination with estrogen and prolactin is involved with the
development and differentiation of the breast and maintenance of pregnancy
34
estrogens effects on cardiovascular system (good things) (2)
improves lipid profile and increases the release of nitric oxide
35
estrogens effects on cardiovascular system (bad things) (2)
increases blood clotting so it increases the chance of venous thrombosus
36
estrogen maintains
bone density, closure of epiphyses
37
estrogen also alters the pattern of fat
deposition
38
one major action of estrogen is to increase the synthesis of what receptor?
progesterone!!
39
at the beginning of the cycle are LH levels low or high?
low
40
LH levels stay constant until late in what phase?
follicular phase
41
FSH levels are low or high at the beginning of the cycle?
low
42
FSH follows a similar pattern as
LH
43
estrogen is low/high at the beginning of the cycle?
low
44
estrogen increaes and increases throughout the _____ phase until about ___ hours before the LH surge
follicular phase, 12 hours
45
there is a 2nd estrogen increase during the ____ phase
luteal
46
estrogen levels fall again as the ________ degenerates
corpus luteum
47
low doses of estradiol exert what kind of feedback on GnRH and LH
a negative feedback
48
estrogen and progesterone together exert a _____ feedback on GnRH and LH
a negative feedback
49
``` levels of estrogen progesterone FSH LH day 1-5 ```
low low low low
50
``` levels of estrogen progesterone LH FSH day 6-10 ```
increases low slight decrease constant (low)
51
``` levels of estrogen progesterone LH FSH day 11-13 ```
increases A LOT nothing rises rises
52
DAY 14
LH surge
53
``` levels of estrogen progesterone LH FSH day 15-25 ```
increases increases drop drop
54
``` levels of estrogen progesterone LH FSH day 26-28 ```
decrease (if not pregnant) decrease (if not pregnant) decrease decrease