Fertilization (ppt) Flashcards
(40 cards)
• union of mature egg cell (ovum) and sperm cell happening in the______ (outer third) of the fallopian tube
ampulla
• resulting in a fertilized ovum known as the_____
zygote
Fertilization
• also termed
conception, fecundation, and impregnation
sperm must undergo 2 processes before fertilization:
Sperm capacitation
Acrosomal Reaction
: the process by which the sperm becomes hypermobile and there is a breakdown of the plasma membrane and exposes the acrosomal membrane/ covering of the sperm head allowing the sperm to bind with the zona pellucida of the ovum.
Sperm capacitation
_______follows capacitation; the acrosomal covering of the head of the sperm contains______.
So as millions of sperms surrounds the ovum, they deposit minute amounts of hyaluronidase in the corona radiata, the outer layer of the ovum, which allows the sperm head to penetrate the ovum
Acrosomal Reaction
hyaluronidase
As soon as the sperm penetrates the____ and makes contact with the vitelline membrane of the ovum, a cellular change occurs in the ovum that inhibits other sperms to penetrate.
zona pellucida
begins when the outer membranes of the sperm and secondary oocyte meet
Fertilization
Fertilization occurs when the (chromosome #)______ is restored a new combination of genetic material from the parents
chromosome diploid number
(46)
: series of mitotic cell division by the zygote
Cleavage
: daughter cells arising from the mitotic cell division of the zygote 2-cell, 4-cell, 8-cell
Blastomeres
: solid ball of cells produced by 16 or so blastomeres;
called the “traveling” form because it is in this form when it migrates thru the fallopian tube and reaches the uterine cavity about 3 to 4 after ovulation.
Morula
: a fluid-filled cavity that reaches the uterine cavity
Blastocyst
IMPLANTATION
• Also called
Nidation
Time: 6 to 9 days after fertilization
Implantation
• Site: upper fundal portion or upper one-third of the uterus
Implantation
Abnormal implantation sites are the fallopian tubes which leads to ____and the lower uterine segment which causes_____
ectopic pregnancy
placenta previa
Stages of Intrauterine Development
- Ovum
II. Embryo
III. Fetus
• From fertilization to 2 weeks
• The period of pre-differentiation of organs.
Ovum
• First 8 weeks
• The period of organ differentiation (organogenesis)
• Most Dangerous Period: A teratogen introduced at this stage may result in severe organ malformation and dysfunction
Embryo
: the dysgenesis of fetal organs as evidenced either structurally or functionally
Teratogenesis
The typical manifestation of____ are restricted growth or death of the fetus, carcinogenesis, and malformation, defined as defects in organ structure or function.
teratogenesis
EMBRYONIC GERM LAYERS
• Ectoderm
• Endoderm
• Mesoderm
Ectoderm
• outer layer; develops into:
- Nervous system
- Hair, nails, skin epidermis, sebaceous and sweat glands
- Salivary glands, mucous membrane of mouth
- Epithelium of nasal oral passage