Fibrinolysis

Question 1

What are the three agents commonly used for fibrinolysis?

Answer 1

Alteplase (Activase), Streptokinase (Streptase), Reteplase (Retavase)

These agents are used to convert plasminogen to plasmin.

Question 2

What is the role of fibrinolytic agents in the body?

Answer 2

They convert plasminogen to plasmin

Plasmin is the active form that dissolves clots.

Question 3

What is a potential risk associated with the use of fibrinolytic agents?

Answer 3

Uncontrolled bleeding

These agents can act anywhere in the body.

Question 4

What does EMS-to-balloon time measure?

Answer 4

Time from first patient contact by EMS to definitive therapy

Definitive therapy is when a catheter passes through the lesion in the affected coronary vessel.

Question 5

Define door-to-balloon time.

Answer 5

Interval between patient presentation to the medical facility and definitive therapy

This measures the efficiency of treatment in the hospital setting.

Question 6

What is door-to-needle time?

Answer 6

Time from patient arrival at the ED to administration of fibrinolytic medication

This is critical for timely treatment of conditions like STEMI.

Question 7

Fill in the blank: Fibrinolytic agents convert plasminogen to _______.

Answer 7

plasmin

Question 8

True or False: The use of fibrinolytic agents is completely safe with no risk of bleeding.

Answer 8

False