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final Flashcards

1
Q

subacute degeneration of the spinal cord results from deficiency of which vitamin?

A

cobalamin (B12)

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2
Q

methotrexate inhibits

A

reductase

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3
Q

obstruction of vessels of which organ could result from a thromboembolus that originates from the left atrium

A

brain

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4
Q

what is an infarct

A

zone of necrosis due to o2 deficiency

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5
Q

which vessels are involved with temporal arteritis

A

temporal

vertebral

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6
Q

fracture of longbones lead to what type of embolism

A

fat embolism

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7
Q

propagation of thrombi occurs in

A

leg veins

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8
Q

pathogenesis of serum sickness

A

immune complex mediated

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9
Q

poison ivy dermatitis is what type of hypersensitivity

A

delayed type

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10
Q

which cells are predominantly found in chronic inflamation

A

macrophages and lymphocytes

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11
Q

tuberculin reaction is

A

delayed hypersensitivity

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12
Q

anti tumorous immunity

A

t-cell mediated

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13
Q

micro element necessary necessary for coagulation?

A

Ca+

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14
Q

what initiates the intrinsic pathway of coagulation?

A

exposure of collagen fibers to blood flow

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15
Q

what clotting factor disorder develops in patient but not parents?

A 
hemophilia A
hemophilia B (aka christmas factor
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16
Q

what does S mean in crest?

A

sclerodactyly

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17
Q

vasculitis can result in

A

infarction

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18
Q

lines of zhan can be found in which part of the cardiovascular system?

A

aorta

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19
Q

glossitis and chelitis are associated with deficiency of which vitamins?

A

pyridoxine (b6)
folic acid
riboflavin (b2)

20
Q

which tissues are permanent

A

cardiac muscle cells

21
Q

superficial interstitial keratitis results from the deficiency of which vitamin?

A

riboflavin (b2)

22
Q

flaky paint

A

kwashiorkor

23
Q

deficiency of which vitamin causes retrograde amnesia

A

thiamine B1

24
Q

not a manifestation of marasmus

A

hyboalbuminemia

25
Q

vitamin K deficiency could result in what pathology?

A

ecchymosis

26
Q

overactivity of which cells play a the most important role in pathogenesis of systemic sclerosis?

A

fibroblasts

27
Q

hemorrhage into the subcutaneous tissue of less than 2 cm in diameter is called

A

purpura

28
Q

xerostomia is a typical manifestation of which disease?

A

sjogrens syndrome

29
Q

stimulation of CD4 t-cells and release of cytokines in the delayed type reaction results in the release of what type of cells?

A

macrophages

30
Q

pemphigus vulgaris is associated with which subtype of hypersensitivity 2 reaction?

A

complement dependent reactions

31
Q

anaphylactic type of hypersensitivity reaction is induced by sensitization of which type of cells?

A

CD4 and Th2 cells

32
Q

which cells play the most important pathogenic role in type 1 hypersensitivity reaction

A

mast cells

33
Q

formation of granuloma is associated iwht which type or subtype of hypersensitivity reactions?

A

delayed type

34
Q

development that is inadequate so that the resulting structure is immature and functionally deficient?

A

hypoplasia

35
Q

revers of normal cell differentiation

A

anaplasia

36
Q

production of new cells but only in quantities needed to meet a particular demand?

A

hyperplasia

37
Q

conversion from one cell or tissue type to another

A

metaplasia

38
Q

lack of organ development

A

aplasia

39
Q

which cancer develops more likely in a female patient with HPV virus if she takes birth control pills

A

cervical carcinoma

40
Q

which of the following tumors is malignant?

A

lymphoma

41
Q

hepatomegaly could be a manifestation of which condition?

A

vitamin A hypervitaminosis

42
Q

which component of vitamin A accounts for potentiating the differentiation of specialize epithelial cells?

A

retinoid acid

43
Q

which statement is correct?

A

anemia of vitamin B12 deficiency improves with folic acid

44
Q

bleeding disorders could result from the deficiency of which vitamin?

A

ascorbic acid

45
Q

which vitamin deficiency could develop in a patient who takes such medications like estrogens and d-penicillinamins?

A

B6 pyridoxine

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