final Flashcards

1
Q

subacute degeneration of the spinal cord results from deficiency of which vitamin?

A

cobalamin (B12)

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2
Q

methotrexate inhibits

A

reductase

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3
Q

obstruction of vessels of which organ could result from a thromboembolus that originates from the left atrium

A

brain

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4
Q

what is an infarct

A

zone of necrosis due to o2 deficiency

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5
Q

which vessels are involved with temporal arteritis

A

temporal

vertebral

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6
Q

fracture of longbones lead to what type of embolism

A

fat embolism

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7
Q

propagation of thrombi occurs in

A

leg veins

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8
Q

pathogenesis of serum sickness

A

immune complex mediated

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9
Q

poison ivy dermatitis is what type of hypersensitivity

A

delayed type

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10
Q

which cells are predominantly found in chronic inflamation

A

macrophages and lymphocytes

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11
Q

tuberculin reaction is

A

delayed hypersensitivity

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12
Q

anti tumorous immunity

A

t-cell mediated

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13
Q

micro element necessary necessary for coagulation?

A

Ca+

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14
Q

what initiates the intrinsic pathway of coagulation?

A

exposure of collagen fibers to blood flow

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15
Q

what clotting factor disorder develops in patient but not parents?

A
hemophilia A
hemophilia B (aka christmas factor
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16
Q

what does S mean in crest?

A

sclerodactyly

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17
Q

vasculitis can result in

A

infarction

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18
Q

lines of zhan can be found in which part of the cardiovascular system?

A

aorta

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19
Q

glossitis and chelitis are associated with deficiency of which vitamins?

A

pyridoxine (b6)
folic acid
riboflavin (b2)

20
Q

which tissues are permanent

A

cardiac muscle cells

21
Q

superficial interstitial keratitis results from the deficiency of which vitamin?

A

riboflavin (b2)

22
Q

flaky paint

A

kwashiorkor

23
Q

deficiency of which vitamin causes retrograde amnesia

A

thiamine B1

24
Q

not a manifestation of marasmus

A

hyboalbuminemia

25
vitamin K deficiency could result in what pathology?
ecchymosis
26
overactivity of which cells play a the most important role in pathogenesis of systemic sclerosis?
fibroblasts
27
hemorrhage into the subcutaneous tissue of less than 2 cm in diameter is called
purpura
28
xerostomia is a typical manifestation of which disease?
sjogrens syndrome
29
stimulation of CD4 t-cells and release of cytokines in the delayed type reaction results in the release of what type of cells?
macrophages
30
pemphigus vulgaris is associated with which subtype of hypersensitivity 2 reaction?
complement dependent reactions
31
anaphylactic type of hypersensitivity reaction is induced by sensitization of which type of cells?
CD4 and Th2 cells
32
which cells play the most important pathogenic role in type 1 hypersensitivity reaction
mast cells
33
formation of granuloma is associated iwht which type or subtype of hypersensitivity reactions?
delayed type
34
development that is inadequate so that the resulting structure is immature and functionally deficient?
hypoplasia
35
revers of normal cell differentiation
anaplasia
36
production of new cells but only in quantities needed to meet a particular demand?
hyperplasia
37
conversion from one cell or tissue type to another
metaplasia
38
lack of organ development
aplasia
39
which cancer develops more likely in a female patient with HPV virus if she takes birth control pills
cervical carcinoma
40
which of the following tumors is malignant?
lymphoma
41
hepatomegaly could be a manifestation of which condition?
vitamin A hypervitaminosis
42
which component of vitamin A accounts for potentiating the differentiation of specialize epithelial cells?
retinoid acid
43
which statement is correct?
anemia of vitamin B12 deficiency improves with folic acid
44
bleeding disorders could result from the deficiency of which vitamin?
ascorbic acid
45
which vitamin deficiency could develop in a patient who takes such medications like estrogens and d-penicillinamins?
B6 pyridoxine