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SES 626-Metabolism > Final Exam Questions > Flashcards

Final Exam Questions Flashcards

1
Q

Triacylglycerol lipolysis in exercising skeletal muscle involves which of the following?

inhibition of perilipin A

activation of hormone sensitive lipase

inhibition of hormone sensitive lipase

activation of phosphodiesterase

A

Activation of hormone sensitive lipase

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2
Q

What effects does epinephrine have on the liver?

A

Stimulates glycogenolysis

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3
Q

What happens to perilipin A and Triacylglycerol lipase during acute exercise?

A

they are phosphorylated

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4
Q

Which of the following best describes the effects of a bout acute exercise on blood glucose?

A

Glucagon levels increase which is associated with an increase in blood glucose

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5
Q

In what way does insulin affect lipid metabolism in adipocytes?

A

Inhibits perilipin A activity

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6
Q

Which of the following would increase fatty acid beta oxidation rate during exercise?

A. GLUT-4 translocation to the cell surface
B. FAT/CD36 translocation to the cell surface
C. Increase phosphodiesterase activity
D. Inhibition of hormone sensitive lipase

A

B. FAT/CD36 translocation to the cell surface

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7
Q

Secretion of which of the following hormones typically decreases during an acute bout of exercise?

A. Glucagon
B. Norepinepherine
C. Epinepherine
D. Insulin

A

Insulin

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8
Q

Which of the following is associated with increased adipocyte lipolysis?

A. Activation of phosphodiesterase
B. Conversion of cAMP to AMP
C. Insulin binding to it’s receptor on an adipocyte
D. Epinepherine binding to it’s receptor on an adipocyte

A

Epinepherine binding to it’s receptor on an adipocyte

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9
Q

What effects does insulin have on the liver?

A

Stimulates glycogenolysis

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10
Q

Place the following steps of the urea cycle in the correct order.

        I.    arginosuccinate synthetase catalyzes the formation of arginosuccinate

        II.   carbamoyl phosphate and ornithine join to form citrulline

        III.  argenine is formed

        IV.  carbamoyl phosphate is formed 

        V.   arginase catalyzes the formation of urea and ornithine
A

4,2,1,3,5

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11
Q

In order for branched chain amino acids (BCAA) to be utilized for energy during exercise, they must first be ___________ which is followed by ___________?

A

Converted to an alpha keto acid, decarboxylation

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12
Q

Oxidation of which of the following amino acids does not seem to increase during endurance exercise?

A. Asparagine
B. Isoleucine
C. Leucine
D. Valine

A

A. Asparagine

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13
Q

Which of the following is true regarding the glucose-alanine cycle?

A. alanine exits the liver, is transported to the muscle, and converted to glucose

B. the amino group carrier in the blood is alanine which is then converted to pyruvate in the liver

C. the amino group carrier in the blood is pyruvate which is then converted to alanine in the liver

D. glucose exits the muscle, is transported to the liver, and converted to alanine

A

B. the amino group carrier in the blood is alaine which is then converted to pyruvate in the liver

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14
Q

In general, acute endurance training exercise is associated with which of the following?

A. decreased proteolysis and increased protein synthesis

B. increased proteolysis and increased protein synthesis

C. increased proteolysis and decreased protein synthesis

D. decreased proteolysis and decreased protein synthesis

A

C. increased proteolysis and decreased protein synthesis

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15
Q

What type of sugar is glucose?

A

Hexose

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16
Q

Which enzyme catalyzes the following reaction?

     ADP + ADP ⇆ ATP + AMP
A

Myokinase

17
Q

How many ATP are broken down in anaerobic glycolysis?

A

2

18
Q

In which reaction of the Kreb’s Cycle is FADH2 generated?

A

Dehydrogenation of succinate

19
Q

Which molecule is the final electron acceptor in the glycerol-phosphate shuttle?

A

NADH

20
Q

Which enzyme catalyzes the conversion of DHAP to G3P in gluconeogenesis

A

Glycerol Phosphate Dehydrogenase

21
Q

Enzymes involved in lipolysis

A

Adipose Triglyceride Lipase
Hormone Sensitive Lipase
Monoglyceride Lipase

22
Q

What are the fates of an amino acid carbon skeleton?

A

Glucose
Fats
Acetyl CoA

23
Q

Which molecule increases PFK during acute exercise?

A

ADP

24
Q

Muscle contraction-induced GLUT-4 translocation involved which enyzme

A

AMPK

25
Q

What does increased GLUT4 do during glycolysis

A

increases substrate

26
Q

What effects does epinephrine have on the liver?

A

Stimulates Glycogenolysis

27
Q

What does conversion of cAMP to AMP indicate?

A

increased adipocyte lipolysis

28
Q

Which hormone decreases during an acute bout of exercise?

A

Insulin

29
Q

What role does fructose 2,6 biphosphate play?

A

Helps regulate glucose metabolism in the liver

SES 626-Metabolism (14 decks)

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