Flashcards in Gallbladder Deck (15):
What kind of disorders might the gallbladder be faced with?
Disorders can involve inflm, infection, stones and tumors
What is inflm of the gallbladder called?
What is the term for precipitates developing in the gallbladder?
What 3 mechanisms often lead to precipitation of stones?
o Abnormal bile composition (ex Inc cholesterol, dec bile salts)
o Bille stasis -> precipitation
o Inflm debris -> nuclei for stone formation
What two offending agents are associated with development of inflm debris?
• E. coli and strep. Faucalis implicated
Mechanism unknown but they alter bile composition
Do genetics play a role
There is suggestion they have an influence but it remains unclear
When do gall stones start causing problems?
When they migrate into a duct
Potential for obstruction
3 types of Gall Stones
Incidence of each?
o Cholesterol stones (80%)
• Bile + inc cholesterol
o Pigment stones (20%)
• Bilirubin and Ca salts
o Mixed stones
Two key MNFTS
o Colic pain (intermittent and radiating)
o Nausea and vomiting (r/t to severe pain)
What could Gall stones MNFTS be misdiagnosed as
Dx of Gall stones
o HX and Px
o Ultrasound, scans (CT, MRI…etc)
NOTE: Stones present may not mean it is the cause of pain... necessarily
Tx if no obstruction present
o Dissolving agents (eg ectigall)
+ pain meds...
Tx if there is an obstruction
Sx (eg retrograde endoscopy)
Tx in severe case