General 5 Flashcards

1
Q

where is dopamine MADE

A

substantia nigra

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2
Q

opsoclonus myoclonus cause and treatment

A

associated with infantile neuroblastoma; tx steroids or ACTH

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3
Q

Ramsay Hunt syndrome

A

herpetic neuritis of geniculate ganglion; affected nerves 7,8

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4
Q

most common CNS tumor in advanced AIDS

A

lymphoma

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5
Q

peak of neuronal PROLIFERATION

A

2nd trimester

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6
Q

peak of neuronal SYNAPTOGENESIS

A

toddler period (and doesn’t conclude until age 30!)

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7
Q

most frequent CNS opportunistic infxn in AIDS

A

toxoplasmosis

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8
Q

slowest of the prion diseases

A

Gerstmann-Straussler-Scheinker

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9
Q

Bell’s palsy most often due to

A

occult HSV

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10
Q

what does tetanus toxin do?

A

blocks GABA and glycine in spinal cord

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11
Q

Anton’s syndrome

A

pts deny blindness; due to b/l PCA involvement

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12
Q

Balint’s syndrome

A

due to basilar involvement (unlike Antons - PCA)

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13
Q

inhalant abuse can lead to

A

polyneuropathy (distal)

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14
Q

Meige’s syndrome

A

blepharospasm and oromandibular dystonia

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15
Q

scanning speech

A

cerebellum injury

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16
Q

aphemia

A

muteness with normal reading, writing, comprehension; due to involvement of Broca’s

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17
Q

opens NMDA receptor

A

glutamate AND glycine

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18
Q

best somatoform prognosis

A

conversion

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19
Q

only drug that is selective GABA reuptake inhibitor

A

tiagabine (gabitril)

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20
Q

GABA-A receptor is what kind of channel?

A

chloride

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21
Q

drug that is equal to BZDs for etoh w/d

A

carbamazepine

22
Q

sign of AVM

A

auscultating head and hearing bruit; sz also common

23
Q

cause of childhood dementia and Parkinsonism

A

Hallervorden-Spatz; iron in basal ganglia, cysteine dioxygenase

24
Q

how to treat lithium DI

A

amiloride with HCTZ

25
mirtazapine MOA
blocks alpha2 presynaptic receptors
26
fungus that causes PNA, invades vessels
Aspergillus
27
funds that causes CNS abscess, liver dz, flu-like infection
histoplasma
28
which gender more commonly has depression?
women
29
cardiac effects of cannabis
tachycardia
30
developed idea of transitional object
Winnicott
31
paranoid-schizoid position
Klein: world split into good and bed elements
32
BPRS used for which disorders?
schizophrenia and psychosis
33
sleep terrors
... have amnesia for the event
34
often associated with retrograde ejaculation
mellaril (thioridazine)
35
NTs affected by MDMA
dopamine AND serotonin
36
elevated ACE in CSF, neuropathies
sarcoidosis
37
hypersomnia followed by psych sx
Kleine-Levin syndrome
38
Alexia without agraphia
Left PCA: selenium of corpus callosum
39
childhood disorder with precuts excavated, lens dislocation, Marfan's habits, MR, scoliosis
Homocystinuria
40
bupropion is a substrate of
2B6
41
___% of striatal dopamine and mitral neurons lost before PD sx arise
60-85
42
triptan MOA
agonists of 1B and 1D
43
helps with chorea in HD
tetrabenazine
44
stiff person syndrome associated with
diabetes, polyendocrinopathy, antibodies to glutamic acid decarboxylase
45
anatomy of semantic memory
inferotemporal lobes
46
anatomy of procedural memory
basal ganglia, cerebellum, SMA
47
anatomy of episodic memory
medial temporal, anterior thalamic nuclei, mammillary bodies, fornix, prefrontal cortex
48
NT involved with LSD
serotonin
49
validity scales of MMPI
lie scale, infrequency scale, suppressor scale
50
MMPI scale used to decrease false positives and false negatives
suppressor scale
51
MMPI scale used to detect malingering
infrequency scale