General sensation Flashcards

(58 cards)

1
Q

Name some types of sensory receptors?

A

Mechanoreceptors
Chemoreceptors
Thermorecepors
Nociceptors

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2
Q

What do chemoreceptors detect?

A

pH

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3
Q

What do nocireceptors respond to?

A

Damaging stimuli

Pain when it enters brain

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4
Q

What receptors have free endings?

A

Nociceptors and cold receptors

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5
Q

What is the receptive field?

A

Respond to stimulus over a specific area

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6
Q

What is Meissner corpuscles?

A

consist of a cutaneous nerve ending responsible for transmitting the sensations of fine, discriminative touch and vibration

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7
Q

A-D

A

A = meissners corpuscle
B = merkles corpuscle
C = pacinian corpuscle
D = ruffini corpuscles

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8
Q

What does meissners corpuscle detect?

A

Light touch

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9
Q

What does merkels corpuscle detect?

A

Touch

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10
Q

What does pacinian corpuscle detect?

A

Deep pressure

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11
Q

What does ruffini corpuscle detect?

A

Warmth

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12
Q

What is a pharmacological receptor?

A

Ach receptor

Protein in the posterior-synaptic membrane

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13
Q

What is a physiological receptor?

A

Whole Sensory terminal

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14
Q

What does the size of the receptor potential encode?

A

Intensity of stimulus

E.g. bigger pressure then bigger potential

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15
Q

What encodes the intensity of stimulus through AP?

A

Frequency of firing of AP

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16
Q

What does the location of the receptive field tell us?

A

Location - Which bit if the skin the stimulus came from

Modality - e.g. mechano receptor

Intensity - number of AP Being fired tells you how strong the stimulus was

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17
Q

What is axon hillock called in efferent neurones?

A

Trigger zone

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18
Q
A

A = small receptive field
B = large receptive field

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19
Q

What areas have a small receptive field?

A

Finger tips and mouth

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20
Q

What areas have a high receptive field?

A

Back

Sparse receptive field

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21
Q

What makes your fingers more sensitive?

A

Acuity

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22
Q

What determines acuity?

A

Density if innervation and size of receptive field

The small receptive field neurones! Fingers have small and will activate more than 1 neurone compared to 1 (e.g. back)

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23
Q

What 3 receptors mediate cutaneous sensation?

A

Abeta
Adelta
C

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24
Q

What do the alpha-beta fibres conduct?

A

Large myelinated

Touch,
Reassure
Vibration

25
What do the alpha-delta fibres conduct?
Small myelinated Cold Fast pain Pressure
26
What are the small myelinated Afferent fibres?
Alpha-delta
27
What do the C fibres conduct?
Unmyelinated fibres Warmth Slow pain
28
What are the unmyelinated Afferent fibres?
C fibres
29
What primary Afferent fibres mediate proprioception?
Aalpha Abeta
30
What are the 2 modes of sensory transmission?
1. Mechanoreceptive Abeta fibres Ipsilateral 2. Thermoreceptive and Nociceptors fibres (A-delta and C) Contralateral
31
Where do the mechanoreceptive fibres synapse?
Cuneate and gracile nuclei
32
When do the mechanoreceptive fibres cross over the midline?
The 2nd order neurones cross over the midline in the brain stem and project to reticular formation, thalamus to cortex
33
Where do the thermoreceptive and Nociceptive fibres synapse?
Dorsal horn
34
What tract do the thermoceptive and nociceptove fibres project up?
Condrolateral spinothalmic tract to reticular for,action to thalamus to cortex
35
What does damage to Dorsal columns cause?
Causes loss of touch, vibration, proprioception below lesion on Ipsilateral side
36
What does damage to anterolateral quadrant cause?
Causes loss of Nociception and temperature sensation below lesion on condralateral side
37
Where is the ultimate termination for sensory information?
Somatosensory cortex of the post central gyrus
38
What areas have a higher representation in the somatosensory cortex?
Finger tips Density of receptors at each location
39
What is the sensory homunculus?
Brains view of the body
40
Can you stimulate sensations along the pathway?
Yes, e.g. funny bone stimulates AP from many neurones
41
What does this show?
Sensory homunculus
42
What are the levels of processing of sensory innervation?
Adaptation Convergence Lateral inhibition Perception
43
What are 2 types of adaptation?
Rapidly adapting Slowly adapting
44
What is the rapidly adapting neurone?
After stimulus it stops and gets used to it
45
What is an example of a rapid adaptation?
Hat on head
46
What is neural convergence (processing)?
Several sensory neurones will synapse on to the same secondary order neurone and it’ll go to cortex
47
What are the pros of convergence?
Saves on neurones
48
What are the disadvantages of convergence?
Reduces acuity Underlies referral sensation (e.g. heart attack feel pain in shoulder and arm)
49
What are types of convergence?
Specific ascending pathways (same receptor Mechano for example) Nonspecific (could be a mix of touch and temp…)
50
What is lateral inhibition in processing if sensory information?
Activation of a sensory input causes synaptic inhibition of its neighbours
51
What is the advantage of lateral inhibition?
Gives better definition boundaries Cleans up sensory information
52
Why don’t all stimulus enter the brain?
Descending inhibitor controls
53
What are the 2 types of inhibition shown here?
Pre synaptic and post synaptic
54
What receptor does analgesia inhibit?
Nociceptive
55
What are the 2 separate forms of inhibition?
Segmental controls Descending controls
56
What does the segmental controls revolve around?
Gate control theory of pain
57
What inhibits the Adelta and C fibres? (Segmental control)
Mechanoreceptive fibres going up the dorsal column The Alpha/beta fibres via the axon collateral
58
Where do the descending inhibits controls come from?
Peri-acqueduct grey matter (PAG)