Genetics Flashcards

1
Q

What stage does Synapsis occur in meiosis ?

A

Prophase I

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2
Q

What genetic configuration disrupts Mendel’s law of genetics?

A

Linked genes on the same chromosome

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3
Q

What are the conditions needed for Hardy Weinberg equations to hold true?

A
  1. no mutations
  2. no natural selection
  3. Random mating
  4. Large Population
  5. no migration
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4
Q

how many generations are required to restore Hardy Weinberg equilibrium if disrupted?

A

1 generation

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5
Q

When can natural selection occur?

A

if there is genetic diversity

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6
Q

How does hardy Weinberg impact allele frequencies?

A

The Hardy-Weinberg theory states that allele frequencies will be UNCHANGING if certain conditions are met

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7
Q

Describe the components of a genome

A

Human genome:
- has 23 pairs of chromosomes (46 total chromosomes), comprised of 22 autosomal pairs and 1 pair of sex chromosomes (XX or XY)
-Each gene has only 1 locus.
There are 4 RNA bases (U, C, G, A) and 64 possible codons.

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8
Q

What is ELISA used for?

A

ELISA (Enzyme-linked imunno absorbent assay)
-ELISA uses fluorescent or enzyme-linked antibodies to find either antigen or other antibodies in a person’s serum

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9
Q

What is western blotting?

A

Western blots use antibodies to detect specific PROTEINS in a given sample of tissue extract.

Gel electrophoresis is used to separate native or denatured proteins by the length and charge of the polypeptide (

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10
Q

What is PCR Amplification ?

A

PCR amplification allows you to take a specific sequence of DNA and make multiple copies of it.

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11
Q

What is FISH (lab technique) used for?

A

FISH can identify a range of mutations including deletions, duplications, aneuploidy, and the presence of derivative chromosomes
(Flourescence in situ hybridization)

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12
Q

What is a test cross?

A

A testcross is used to determine whether an individual with a dominant trait (and an unknown genotype) is heterozygous or homozygous

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13
Q

What is a back cross ?

A

back”cross implies that the individual is crossed “back” to a member of the previous generation

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14
Q

What is the result of inbreeding?

A

inbreeding results in an increase in the frequencies of all homozygous genotypes,

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15
Q

What is effect of assortive mating ?

A

while assortive mating only increases the frequency of homozygosity in the trait being selected for

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16
Q

What can occur as a result of reproductive isolation ?

A

SPECIATION
reproductive isolation will cause species to diverge and create New species

17
Q

what type of cell continually divides and gets replaced ?

A

intestinal epithelial cell

18
Q

How do viruses gain entry into a cell ?

A

all viruses gain entry by recognition of cell surface PROTEINS (receptors) by viral proteins

19
Q

what is the result of endocytosis ?

A

Endocytosis results in material being internalized into the endosome and lysosomes for destruction

20
Q
A