Gential System Flashcards

(51 cards)

1
Q

what happens to the inguinal canal after process vaginalis takes place?

A

it closes around the spermatcord

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2
Q

what allows the testes to move transabdominally

A

atrophy of the mesonephric ducts

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3
Q

what week have the testes descended?

A

week 26

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4
Q

hysterosalpinography is used for what

A

to diagnose if there is something wrong in the uterine tubes or uterus, for someone who has had multiple miscarriages

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5
Q

double uterus?

A

inferior parts of the paramesonephric duct fails to fuse can have double or single vagina

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6
Q

bicarbonate uterus means what

A

duplication of the superior part of the uterus

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7
Q

unicornate ureters

A

one paramesonephric duct fails to form, leaving only one uterine tube

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8
Q

double utuers refers to?

A

failure of the inferior parts of the paramesonephric ducts to fuse.

have double or single vagina

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9
Q

where does the urethra open in agenesis of external genitalia

A

into the perineum near the anus

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10
Q

anamalies of the uterine tube, uterus and vagina are due to what?

three things

A

incomplete fusion of the paramesonephric duct

failure for parts to develop

incomplete canalization of the vagina plate to form the vagina

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11
Q

what is the most common cause of female pseudohermaphroidism

A

ACH-adrenocortical hyperplasia

the labia fuses and there is hypertrophy of the clitoris making it look like a penis but genotype is still 46XX

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12
Q

what is male pseudohermaphroditism due to? (46 XY)

A

due to the inadequate production of testosterone and MIS by fetal testes.

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13
Q

what is a true hermaphrodite?

A

someone who has ovarian AND testicular tissue in the same or opposite gonads

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14
Q

are ovaires and testes functiona in true hermaphrodites?

A

no

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15
Q

True hermaphroditism percentages

A

70- 46Xx
20- 46 XX/46XY
10- 46xy

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16
Q

When can you truly document if a fetus is a boy or girl?

A

22-36 weeks

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17
Q

Genotype is established when

A

At fertilization

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18
Q

Embryo is sexually indifferent in what weeks

A

Week 1 to week 6

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19
Q

Phenotypic sexual differentiation begins when

A

Week 7

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20
Q

The three sources that the gonads derive from

A

Mesothelium (lines posterior abdominal wall)

Mesenchyme

Primordial germ cells

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21
Q

Initial period of development is called?

A

Sexual development or indifferent stage

22
Q

What happens in week 5 in regards to the gonads

A

The mesothelium of the medial side of the mesonephros thickens, it prliferates and makes the gonadal ridge

23
Q

Gonadal cords do what

A

Grow into the underlying mesenchyme

24
Q

When do cells enter the underlying mesenchyme and are incorporated with the gonadal cords

25
Male phenotype is determined by what
TDF- testies determining factor
26
Due to TDF what happens to the gonadal cords
They become seminiferous cords
27
What determines male sexual differntiation
Testosterone and ADH
28
Primary female differentiation depends on what
Not hormones! It will happen even if ovaries are not present
29
TDF makes the gonadal cords do what in the medulla
Extend and form rete testes
30
What happens to the primary sex cord in men
It extends into the medulla and becomes the tunica albugenia
31
Seminiferous tubules are separated by mesenchyme that has what
Leydig cells
32
When do leydig cells secrete the androgen hormones testosterone and Androstenedione, the hormones that induce masculine differentiation of mesonephric ducts and external genitalia
Week 8
33
aMH-
Antimullerian hormone
34
Female duct is called? Make duct is called?
Mullerian Wollfian
35
What produces AMH
Sertoli cells
36
What does AMH do
It surprises the paramsonephric ducts from developing to form the uterus and uterine tube
37
Seminiferous tubules remain solid with no lumen until when
Puberty
38
What are the two cells in the walls of the seminiferous tubules
Sertoli and spermatogonia Seritoli comes from surface epithelium of testes Spermatogonia comes from primordial germ cells
39
When do the gonadal cords appear for female | And they extend to form what
Week 10 form rete ovarii
40
What week do the cortical cords break up into isolated cell clusters and form ongoing covered in follicular cells
Week 16
41
Oocytes (primary)
5 month 7million Birth- 2 million Puberty 40,000
42
When do the genital ducts develop , mullerian or wolffian
Week 5 or 6
43
When do leydig cells produce testosterone? | Sertoli - aMH?
Week 8 week 7/6
44
hCG stimulates what
Testosterone production
45
Testosterone does what to the mesonephric ducts
Induces them to become highly convoluted and form epididymis
46
In the absence of aMH what happens
Müllerian ducts form
47
Myometrium comes from
Splanchnic mesenchyme
48
Urogenital sinus and vagina are separated by?
Hymen
49
Gartners duct,
Remnants of mesonephric duct in adult women
50
Remnants of the mesonephric tubules in women are
Epoophron and paroophoron
51
Genital tubercal develops from proliferation of mesenchyme when
Week 4