Geriatrics/Palliative Care/Oncology Flashcards

(51 cards)

1
Q

what does alzheimers cause in the brain

A

cerebral atrophy in the cortex and hippocampus

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2
Q

1st and 2nd line management for alzheimers

A

1st: AchE inhibitors e.g. donepezil and rivastigmine
2nd: NMDA antagonist (memantine)

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3
Q

dementia with visual hallucinations

A

lewy body

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4
Q

dementia with a stepwise progression

A

vascular

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5
Q

gradual onset dementia at a young age with preserved memory and visuospatial skills

A

frontotemporal

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6
Q

why should you check the FBC, U&E, LFT, TFT, Ca, Glucose, B12 and folate in dementia

A

to check for reversible causes

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7
Q

what medication increases mortality in dementia

A

antispychotics

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8
Q

behavioural change and dementia in middle age

A

picks disease

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9
Q

reduced conscious level and psychotic sx

A

delirium

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10
Q

name one cause of delirium

A

constipation

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11
Q

which score is used to assess frailty

A

PRISMA-7

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12
Q

1st and 2nd line management of acute confusional state

A

1st: treat underlying cause and environment
2nd: haloperidol

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13
Q

which two tools assess medication risk benefit

A

STOPP and START

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14
Q

which score assesses pressure ulcers

A

waterlow score

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15
Q

management of pressure ulcers

A

dressing
analgesia
nutritional assessment
abx only if infection

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16
Q

which medication worsens delirium

A

benzos e.g. lorazepam

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17
Q

GI disturbance, dizziness, confused, arrhythmias, blurred yellow vision precipitated by renal failure or low K

A

acute digoxin toxicity

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18
Q

which medication predisposes gout

A

thiazides e.g. indapamide

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19
Q

which sedating medication should you avoid in parkinsons

A

haloperidol - use lorazepam instead

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20
Q

if pain is uncontrolled, how much should you increase morphine by

A

30-50%

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21
Q

what is the breakthrough dose of morphine

A

1/6th the daily dose

22
Q

converting from oral to SC morphine

23
Q

converting from codeine to morphine

24
Q

converting from oral morphine to diamorphine

25
which opioids should you use in CKD
bupenorphine, fentanyl
26
which opioid should you use in mild renal impairment
oxycodone
27
treatment of nausea caused by gastric dysmotility/statis
dopamine antagonist
28
treatment of intracranial nausea
cyclizine
29
treatment of headache caused by raised ICP
dexamethasone
30
treatment of hiccups
chlorpromazine / haloperidol
31
3 treatments for metastatic bone pain
analgesia, bisphosphonates, radiotherapy
32
treatment of a painful mouth
benzydamine hydrochloride mouthwash
33
treatment of respiratory secretions and bowel colic
muscarinic receptor antagonists e.g. hyoscine bromide
34
CA153
breast cancer
35
CA125
ovarian cancer
36
CA199
pancreatic cancer
37
CEA
colorectal cancer
38
AFP (2)
hepatocellular carcinoma teratoma
39
PSA
prostate cancer
40
which other marker is associated with prostate cancer
BRAC2
41
S-100 (2)
melanoma schwannoma
42
Bombesin (3)
SCLC gastric cancer neuroblastoma
43
FAP
gardners syndrome
44
HNPCC
lynch syndrome
45
what condition can you see sinus invertus
kartagener
46
management of neoplastic spinal cord compression
immediate oral dexamethasone urgent MRI of whole spine
47
management of SVC obstruction
dexamethasone
48
where does SCLC metastasise to
spine
49
which lung cancer has the highest association with smoking
squamous cell
50
where does breast cancer metastasise to
bone
51
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