GI

Question 1

Oral manifestations of GI disease can

Answer 1

• precede onset
• Present during Disease
• Persist afterwards
• Reflect systemic alterations secondary to disease

Question 2

Parotid Gland cell type

Answer 2

Mainly serous acini

Question 3

Sublingual gland cell type

Answer 3

Mainly Mucous acini

Question 4

Submandibular main cell type

Answer 4

Mixed

So are minor glands

Question 5

Sialadenitis (inflammatory salivary gland lesions) symptoms

Answer 5

Dry mouth
Swelling
Pain

Question 6

Sialadenitis (inflammatory salivary gland lesions) Conditions

Answer 6

Sialoliths
Mumps
Sarcoidosis
Sjogren syndrome

Question 7

Sjogren Syndrome

Answer 7

Autoimmune disease mostly female 40-50

Question 8

Sjogren symponste

Answer 8

Dry mouth, dry eyes, keratoconjunctivitis sicca

Question 9

During sjogren ______ inflate

Answer 9

Intense lymphocytic inflation

Question 10

Sjogren patients have an increased risk for

Answer 10

Lymphoma

40x

Question 11

What is going to be enlarged in sjogren

Answer 11

Parotid

Unilateral or bilateral

Question 12

Primary Sjogren

Answer 12

Only has SS

Question 13

Secondary Sjogren syndrome

Answer 13

Occurs in setting of other autoimmune disease

Rheumatoid archivists SLE etc

Question 14

What salivary gland is most affected by gland tumors

Answer 14

Parotid 75% of total SG

75% benign

Question 15

Pleomorphic Adenoma ____ occur in _____gland

Answer 15

60%

Parotid

Question 16

Pleomorphic Adenoma tumor will be

Answer 16

Lobulated
Firm 
Encapsulated 
Can undergo malignant transformation 
Very slow growth

Question 17

Warthin Tumor

Answer 17

Parotid Gland lesion
Male predilection
10% bilateral

Question 18

Warthin Tumor is assocaited with

Answer 18

Smoking

Question 19

Warthin Tumor may present

Answer 19

Bilateral

At same time or at different times

Question 20

Mucoepidermoid Carcinoma is the most common

Answer 20

Malignant SG tumor

Question 21

Mucoepidermoid Carcinoma affects which glands

Answer 21

Parotid and minor glands

Question 22

Mucoepidermoid Carcinoma may appear _____ due to _____ and _____

Answer 22

Bluish

Mucin and cystic growth pattern

Question 23

Esophageal obstruction mechanical

Answer 23

Post inflammatory fibrosis/stenosis

Question 24

Esophageal obstruction functional

Answer 24

Discoordinated musclar contractions or spasms diverticula may result; achalasia

Question 25

Esophageal varices

Answer 25

Arise due to portal hypertension. Seen in 40% of cirrhosis patients. Often asymptomatic but rupture can result in massive hemorrhage/death

Question 26

Esophagitis extrinsic agents

Answer 26

``` Chemical Iatrogenic Infections Trauma Heavy smoking ```

Question 27

Esophagitis Intrinsic

Answer 27

Reflux (GERD)

Question 28

Iatrogenic causes

Answer 28

Chemotherapy, radiation, graft versus host disease

Question 29

Esophagealsquamous cell carcinoma

Answer 29

Smoking and alcohol use | Males but super prevalent in African American men

Question 30

Esophageal Adenocarcinoma

Answer 30

Associated with GERD Lower Third Males 7:1 Often detected at late stage

Question 31

Squamous cell cancer of the esophagus affects ____ of the esophagus

Answer 31

Mid 1/3

Question 32

What cancer will you find a keratin pearl

Answer 32

Squamous cell cancer

Question 33

Esophageal adenocarcinoma occur mostly in

Answer 33

The distasteful 1/3 of te esophagus

Question 34

Gastritis

Answer 34

Acute abrupt transient variable pain may note ulceration

Question 35

Autoimmune gastritis is the loss of _________ cells,Decrease __________, Decreased ________absorption, _________anemia

Answer 35

Particularly cells Intrinsic factor B12 absorption Pernicious anemia

Question 36

Acute gastritis pathogenesis

Answer 36

``` Cigarettes Alcohol Stress Ischemia NSAIDs ```

Question 37

Acute Gastritis Pathology

Answer 37

punctuate hemorrhage, erosion | Edema, acute inflammation

Question 38

Chronic gastritis usually caused by

Answer 38

Helicobacter pylori 90% 10% autoimmune (pernicious anemia)

Question 39

Chronic Gastritis pathology

Answer 39

Atrophic epithelium Chronic inflammation Intestinal metaplasia

Question 40

Helicobacter Pylori

Answer 40

Gram - bacillus

Question 41

Helicobacter pylori is found in ________, ___________

Answer 41

65% gastric ulcers | 85-100% duodenal ulcers

Question 42

Peptic ulcer complications

Answer 42

Intractable pain Hemorrhage Perforation Obstruction edema fibrosis

Question 43

Tropical spruce

Answer 43

Aerobic bacteria Small intestine malabsorption diarrhea

Question 44

Abetalipoproteinemia

Answer 44

Transepithelial Transport defect ( mono and triglycerides )

Question 45

Gluten sensitivity

Answer 45

Hypersensitive to gliadin

Question 46

Celiac morphology

Answer 46

Blunted villi | Inflammatory infiltrate

Question 47

Anemia

Answer 47

``` Deficiency: Iron Pyridoxine Folate B12 ``` Bleeding from VIt k deficiency

Question 48

Amenorrhea

Answer 48

Impotence and infertility: generalized malnutrition

Question 49

Osteopenia, tetany

Answer 49

Defective Ca, Mg, VIt D and protein absorption

Question 50

Deficiencies A and B12

Answer 50

Peripheral neuropathy nyctalopia (decreased VIt A)