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Path E3 > GI > Flashcards

GI Flashcards

1
Q

Oral manifestations of GI disease can

A
  • precede onset
  • Present during Disease
  • Persist afterwards
  • Reflect systemic alterations secondary to disease
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2
Q

Parotid Gland cell type

A

Mainly serous acini

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3
Q

Sublingual gland cell type

A

Mainly Mucous acini

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4
Q

Submandibular main cell type

A

Mixed

So are minor glands

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5
Q

Sialadenitis (inflammatory salivary gland lesions) symptoms

A

Dry mouth
Swelling
Pain

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6
Q

Sialadenitis (inflammatory salivary gland lesions) Conditions

A

Sialoliths
Mumps
Sarcoidosis
Sjogren syndrome

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7
Q

Sjogren Syndrome

A

Autoimmune disease mostly female 40-50

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8
Q

Sjogren symponste

A

Dry mouth, dry eyes, keratoconjunctivitis sicca

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9
Q

During sjogren ______ inflate

A

Intense lymphocytic inflation

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10
Q

Sjogren patients have an increased risk for

A

Lymphoma

40x

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11
Q

What is going to be enlarged in sjogren

A

Parotid

Unilateral or bilateral

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12
Q

Primary Sjogren

A

Only has SS

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13
Q

Secondary Sjogren syndrome

A

Occurs in setting of other autoimmune disease

Rheumatoid archivists SLE etc

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14
Q

What salivary gland is most affected by gland tumors

A

Parotid 75% of total SG

75% benign

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15
Q

Pleomorphic Adenoma ____ occur in _____gland

A

60%

Parotid

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16
Q

Pleomorphic Adenoma tumor will be

A 
Lobulated
Firm 
Encapsulated 
Can undergo malignant transformation 
Very slow growth
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17
Q

Warthin Tumor

A

Parotid Gland lesion
Male predilection
10% bilateral

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18
Q

Warthin Tumor is assocaited with

A

Smoking

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19
Q

Warthin Tumor may present

A

Bilateral

At same time or at different times

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20
Q

Mucoepidermoid Carcinoma is the most common

A

Malignant SG tumor

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21
Q

Mucoepidermoid Carcinoma affects which glands

A

Parotid and minor glands

22
Q

Mucoepidermoid Carcinoma may appear _____ due to _____ and _____

A

Bluish

Mucin and cystic growth pattern

23
Q

Esophageal obstruction mechanical

A

Post inflammatory fibrosis/stenosis

24
Q

Esophageal obstruction functional

A

Discoordinated musclar contractions or spasms diverticula may result; achalasia

25
Q

Esophageal varices

A

Arise due to portal hypertension. Seen in 40% of cirrhosis patients. Often asymptomatic but rupture can result in massive hemorrhage/death

26
Q

Esophagitis extrinsic agents

A 
Chemical
Iatrogenic
Infections
Trauma
Heavy smoking
27
Q

Esophagitis Intrinsic

A

Reflux (GERD)

28
Q

Iatrogenic causes

A

Chemotherapy, radiation, graft versus host disease

29
Q

Esophagealsquamous cell carcinoma

A

Smoking and alcohol use

Males but super prevalent in African American men

30
Q

Esophageal Adenocarcinoma

A

Associated with GERD
Lower Third

Males 7:1

Often detected at late stage

31
Q

Squamous cell cancer of the esophagus affects ____ of the esophagus

A

Mid 1/3

32
Q

What cancer will you find a keratin pearl

A

Squamous cell cancer

33
Q

Esophageal adenocarcinoma occur mostly in

A

The distasteful 1/3 of te esophagus

34
Q

Gastritis

A

Acute abrupt transient variable pain may note ulceration

35
Q

Autoimmune gastritis is the loss of _________ cells,Decrease __________, Decreased ________absorption, _________anemia

A

Particularly cells
Intrinsic factor
B12 absorption
Pernicious anemia

36
Q

Acute gastritis pathogenesis

A 
Cigarettes 
Alcohol 
Stress
Ischemia
NSAIDs
37
Q

Acute Gastritis Pathology

A

punctuate hemorrhage, erosion

Edema, acute inflammation

38
Q

Chronic gastritis usually caused by

A

Helicobacter pylori 90%

10% autoimmune (pernicious anemia)

39
Q

Chronic Gastritis pathology

A

Atrophic epithelium
Chronic inflammation
Intestinal metaplasia

40
Q

Helicobacter Pylori

A

Gram - bacillus

41
Q

Helicobacter pylori is found in ________, ___________

A

65% gastric ulcers

85-100% duodenal ulcers

42
Q

Peptic ulcer complications

A

Intractable pain
Hemorrhage
Perforation
Obstruction edema fibrosis

43
Q

Tropical spruce

A

Aerobic bacteria

Small intestine malabsorption diarrhea

44
Q

Abetalipoproteinemia

A

Transepithelial Transport defect ( mono and triglycerides )

45
Q

Gluten sensitivity

A

Hypersensitive to gliadin

46
Q

Celiac morphology

A

Blunted villi

Inflammatory infiltrate

47
Q

Anemia

A 
Deficiency:
Iron 
Pyridoxine
Folate
B12

Bleeding from VIt k deficiency

48
Q

Amenorrhea

A

Impotence and infertility: generalized malnutrition

49
Q

Osteopenia, tetany

A

Defective Ca, Mg, VIt D and protein absorption

50
Q

Deficiencies A and B12

A

Peripheral neuropathy nyctalopia (decreased VIt A)

Path E3 (8 decks)

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