GI Qs Flashcards
When to give albumin for SBP?
Cr>1
Bili>4
BUN>30
Gold standard for diagnosing PSC? Findings?
cholangiography
segmental bile duct fibrosis with saccular dilatation of normal intervening areas, resulting in the characteristic “beads on a string” appearance
Asymptomatic gallbladder polyp over 1 cm. Management?
gallbladder polyp larger than 1 cm is an indication for cholecystectomy, even if the patient is asymptomatic.
Treatment if Crohn’s Disease in pregnant patient?
TNFa
treatment of functional dyspepsia when symptoms do not respond to proton pump inhibitor or H2-blocker therapy?
TCA
When to screen a patient with UC or Crohn’s disease for colon cancer?
every 1 to 2 years beginning after 8 to 10 years of disease.
When to ablate Barrett’s esophagus?
Only for HIGH GRADE displasia
Serum antimitochondrial antibody is present in 90% to 95% of patients with?
Primary biliary cholangitis
When should a hepatocellular adenoma be surgically resected?
> 5 cm or that exhibit β-catenin nuclear reactivity
Candida esophagitis should be treated with?
fluconazole (Not nystatin)
Patient with a hx of endometrial CA and family history of 2 members with colon cancer - when to begin screening colonoscopy?
at risk for Lynch syndrome so:
every 1 to 2 years beginning at age 25 years, or 2 to 5 years earlier than the youngest age at diagnosis of colorectal cancer if the affected relative was younger than 25 years old.
When to treat hep B? With what?
elevated serum ALT level and HBV DNA level > 10,000 IU/mL
pegylated interferon or entecavir
MELD score that warrant liver transplant evaluation?
15+
Milan criteria?
Up to three hepatocellular carcinoma tumors ≤3 cm or one tumor ≤5 cm are best treated with liver transplantation
sorafenib - used to treat? When to start?
HCC
Childs A/B
performance status,
+vascular, lymphatic, or extrahepatic spread of the tumor.
Side effects of metoclopramide?
hyperprolactinemia, galactorrhea, and a variety of neurologic symptoms such as tardive dyskinesia
Drug shown to improve transplant-free survival in non–acetaminophen-related acute liver failure in patients with grade I or II hepatic encephalopathy?
NAC
classic presentation of eosinophilic esophagitis?
young man with solid-food dysphagia that requires endoscopy for removal.
Pegylated interferon is contraindicated in acute hepatitis B because?
risk of exacerbating liver inflammation
Management of acute hepatitis B?
If liver dysfunction – antivirals. If no liver dysfunction – serial LFTs
Peutz-Jeghers syndrome (PJS) - transmission? Type of polyp?
autosomal dominant; hamartomatous polyposis syndrome
Lynch syndrome - transmission? Type of polyps?
germline mutation in a mismatch repair gene. Adenomatous polyps.
Familial adenomatous polyposis (FAP) - transmission? Types of polyps?
Autosomal dominant; is characterized by tens to thousands of adenomatous colorectal polyps.
Types of serrated polyps?
hyperplastic polyps (when small and located in the rectosigmoid colon, are believed to impart no risk to the patient) Sessile serrated polyps and traditional serrated adenomas, are precancerous lesions