giant cell Flashcards
(7 cards)
1
Q
Giant Cell arthritis/ PMR gene
A
HLA DRB104 Northern Europeans
2
Q
Histology GCA
A
panarteritis
giant cell granulomas
disruption internal elastic intima
skip lesions
3
Q
diagnosis GCA
A
atleast 3/5 age onset>50 headache tenderness temporal increased esr histological changes
4
Q
PMR features
A
shoulder and neck region pain and stiffness
pain worse movement night and early am
stiff
5
Q
PMR criteria
A
age greater than 50
aching both shoulders
abnormal crp
6
Q
Fibromyalgia pathogenesis
A
Normal descending inhitory tone from brain stem to dorsal horn reduced- due to serotonin and Noradreneline dysfunction
7
Q
fibromyalgia manegement
A
graded exercise
cognitive behavioural theraphy
TCAs
