Rheumatoid Flashcards
(12 cards)
major cause of mortality RA patients
Cardiovascular
2 ILD types in RA
UIP- peripheral honeycombing + cystic airpspaces
NSIP- diffuse groundglass changes
Large granular lymphocyte fts
neutropenia
lymphocytosis
Rheumatoid factor
ab against the Fc portion of IGG
allele for anti ccp
hladrb104 (poor prognosis greater erosions)
palindromic rheumatism
intermittent episodes of arthritis and periarthritis
remitting seronegative symmetricsynovitis with pitting edema syndrome
af, anti ccp negative
edema of dorsum of hand
tenosynovitis
?paraneoplastic
Leflunomide mech action
inhibits dihydro orotate dehydrogenase
decreased pyrimidines
tofacitinib
Jak inhibitor
when resistant to Methotrexate
most suggestive feature of spinal canal stenosis
paraethesia on weight bearing.
arthrisitis in joint most suggestive of haemochromatosis
metacarpophalyngeal joint.
most exacerbate gout
Beer
