inflammatory myositis

Question 1

rash in dermatomyotisis

Answer 1

gottren papules (erythematous rash over over mtps + PIP)
Helitrope rash upper eye lids
shawl sign :chest and back shawl area

Question 2

EMG in myositis

Answer 2

spontaneous fibrillations
complex repetitive discharges
low amplitude

Question 3

Myositis abs

Answer 3

Anti mi2- most common
anti jo 1 - anti synthetase
anti signal recognition- severe myositis
anti TIF gamma gamma
anti MDA 5- anti melanoma differentiation association protein (mainly Japanese)

Question 4

Jo 1 associated myositis

Answer 4

acute onset.

assoiated with ILD

Question 5

anti nuclear abs in scleroderma

Answer 5

sCL 70- predictive of ILD
RNA pol- associated with renal crisis
u1 rnp: mixed
pm scl: myositis

Question 6

major cause of death in scleroderma

Answer 6

lung fibrosis

Question 7

characteristic of patients with severe ILD

Answer 7

Black race
mae sex
primary myocardial disease
elevated CK

Question 8

histology of ILD I scleroderma

Answer 8

mainy Non specific interstitial pneumonitis- ( HRCT ground glass and fine fibrosis)

Question 9

who to treat with lung disease

Answer 9

fvc <70%

hrct - extent< 20%

Question 10

upper GIT in scelroderma

Answer 10

esophageal reflux commoon

Question 11

management of raynauds

Answer 11

ca blockers
ace
fluoxetine
prostacyclin infusions