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Flashcards in Glycolysis Deck (42)
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1

Glycolysis aka

Embden-Myerhof pathway

2

Glycogen converts _______ into ______.

One 6-carbon glucose
Two 3 carbon pyruvates

3

Glycolysis happens in which cells

All cells of the body

4

_______cells do not have mitochondria to finish the rest of cellular respiration.

Red blood cells

5

Glycolysis takes place in

cytosol/cytoplasm

6

What are the key enzymes in glycolysis?

hexokinase/glucokinase
phosphofructokinase
Pyruvate kinase

7

What is the rate limiting step in glycolysis?

phosphofructokinase

8

What are the two phases of glycolysis?

Preparatory (investing) phase - 1st 5 steps
Pay off phase - last 5 steps

9

Step two of glycolysis is conversion of what?

Glucose-6-phosphate to fructose 6 phosphate

10

What is the enzyme for step two?

phosphoglucose isomerase (changes spatial arrangement)

11

Step one of glycolysis converts what?

Glucose into glucose-6-phosphate

12

What is the enzyme used in step one?

glucokinase in liver
Hexokinase in all other cells

13

Is step one reversible or irreversible?

irreversible

14

Does step one use ATP?

yes

15

Which step in glycolysis is the most important rate limiting step? What happens?

Step 3 - conversion of fructose-6-phosphate into fructose-1,6-bisphosphate

16

What happens in step 4?

Fructose-1,6-bisphosphate converters into glyceraldehyde-3-phosphate and dihydroxyacetone phosphate (DHAP)

17

What enzyme is used in step 4?

aldolase

18

What enzyme converts DHAP to glyceraldehyde-3-phosphate? Step 5

Trios phosphate isomerase

19

Which steps use ATP in the investing phase?

Step 1 and 3

20

Step 6 converts what two things using which enzyme?

Glyceraldehyde-3-phosphate to 1,3 bisphosphoglycerate
Enzyme: G3P dehydrogenase

21

What is used in step 6?

NAD+ and Pi

22

Step 7 converts 1,6 bisphosphoglycerate to3-phosphoglycerate suing what enzyme?

phosphoglycerate kinase

23

Step 7 is known as the _________ point. Why?

Break even
2ATP were used and 2 ATP produced

24

Step 8 converts 3-phosphoglycerate to 2-phosphoglycerate using which enzyme?

phosphoglycerate mutase

25

Step 9 converts 2-phosphoglycerate to phosphoenolpyruvate using which enzyme? Removes what molecule?

Enolase
water

26

What is the enzyme in step 10?

pyruvate kinase

27

How many ATP are created in step 10?

2 ATP

28

Hexokinase is an allosterically regulated enzyme. Which is inhibited by it's product:

Glucose-6-phosphate

29

What would happen if there were too much glucose-6-phosphate in the cell?

The cell would swell

30

Glucokinase if found in the _____ and activated by _____. It is inhibited by what?

Liver
Insulin
Fructose-6-bisphosphate