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My NBCE - Biochemistry - Carbohydrate Metabolism > Sorbitol > Flashcards

Flashcards in Sorbitol Deck (7)
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1

Glucose can be converted to sorbitol via the enzyme:

aldose redutase

2

Sorbitol is the _____________ of glucose

Alcohol counterpart

3

What can convert sorbitol to fructose?

Sorbitol dehydrogenase

4

Sorbitol that converts to fructose can then enter which pathway? How?

Glycolysis
Fructose converted to fructose 1-phosphate -->glyceraldehyde

5

Examples of tissue that LACK sorbitol dehydrogenase:

Lens, retina, and Schwann cells

6

Sorbitol does what to cells? Why?

Draws water in - osmotically active

7

Sorbitol can damage the lens, retina, and nerves because it is osmotically active. This causes what?

Premature cataracts
Retinopathy
Peripheral neuropathy