BACTE_H.ducreyi Flashcards
(31 cards)
This type of lesion begins as a papule and then ulcerates, its edges rise, resembling the lesions of condylomata acuminata and secondary syphilis.
Papular chancroid
in part circumferential mid-esophageal ulcer extending to the distal portion in the presence of normal squamo-columnar junction.
serpiginous
have irregular and folding edges, with a purulent background, hence the name “soft” chancre.
Chankers
H. ducreyi
Men - lesions are found in the
internal surface of the prepuce and the frenulum.
H. ducreyi
Women lesions are found in the
labia and perianal area
Suppuration of the regional lymph nodes (inguinal) occur and is usually unilateral. In untreated cases, the involved lymph nodes become matted forming a unilocular
suppurative bubo.
Laboratory Diagnosis recommended for buboes that are fluctuant and tender
Needle aspiration and/or incision and drainage
Mueller Hinton-based CAP supplemented with
1% IsoxVitalex + 3 µg / ml Vancomycin
Heart-Infusion- based Agar supplemented with
10% Fetal Bovine Serum + 3 µg / ml Vancomycin
Laboratory Diagnosis Gold Standard
Culture
Laboratory Diagnosis Culture Specimen:
Scrapings from the base of the lesion
The media are incubated at
35 ° C in 3 to 5% CO2 (microerophilia), with high humidity, observing the plates daily for 10 days
most common cause of genital ulcer disease (GUD)
Chancroid
Resistant to treatments of
Trimethoprim-Sulfamethoxazole & Tetracycline, Ampicillin and amoxicillin
Beta lactamase- mediated resistance to
Ampicillin and amoxicillin
Chancroid Bacillus of Ducrey’s Bacterium
Hemophilus ducreyi
It is the causative agent of a highly contagious venereal disease known as
Chancroid or Soft Chancre
The first study linking this disease with the agent Hemophilus ducreyi was published in
1889
published in 1889 by
Auguste Ducrey.
Gram-stained smears of exudates taken from the
edge of the lesion
Gram (-) intracellular bacilli arranged like a
school of red fish
In culture: Small, flat, smooth and translucent to opaque at
48-72 hours
plays an important role in transmission
Prostitution
the only known reservoir host;
Man
