Granulopoiesis

Question 1

Key regulators of Granulopoiesis

Answer 1

GM-CSF
G-CSF
IL-5 (eosinophils)
IL-3 & IL-4 (basophils)

Question 2

Enumerate Granulopoietic cells from immature to mature

Answer 2

Myeloblast
Promyelocyte
Myelocyte
Metamyelocyte
Band/Stab
Polymorphonuclear Neutrophil

Question 3

What are the CD markers present in Myeloblast

Answer 3

CD34
CD55 (increased)

Question 4

CD marker/s present in Promyelocyte

Answer 4

CD66b

Question 5

CD marker/s not present in Promyelocyte

Answer 5

CD34
CD55 (decreased)

Question 6

What stage in Granulopiesis is the last stage capable of mitosis and is the morphologically recognizable stage?

Answer 6

Myelocyte

Question 7

CD markers present in Myelocyte

Answer 7

CD11
CD24
CE66a

Question 8

CD markers not present in Myelocyte

Answer 8

CD45r
CD117

Question 9

Juvenile cell

Answer 9

Metamyelocyte

Question 10

CD marker present in Metamyelocyte

Answer 10

CD16

Question 11

First stage of Granulopoiesis that is normally found in the peripheral circulation

Answer 11

Band/Stab

Question 12

CD markers present in Band

Answer 12

CD35
CD87

Question 13

CD markers not present in Band

Answer 13

CD18
CD49d
CD64

Question 14

CD markers present in PMN Neutrophil

Answer 14

CD10
CD14