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MRCP Part 2 and PACES > GUM > Flashcards

Flashcards in GUM Deck (7)
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1
Q

Features of syphillis infection

A

Trepanoma palladum - spirochete bacteria
(potential for TLS type reaction with endotoxin release)

chronic infection can lead to tertiary neurosyphillis

Painless chancre primary presentation - not painful

2
Q

Treatment of syphillis

A

IM penicillin
Azithromycin 2g once - effective and no comps
Ciprofloxacin - 3 days - compliance issues
Doxycyclin - 14 days - compliance

3
Q

New onset seborrheic dermatitis + travel history - what do you think of

A

HIV

80% prevelance in HIV Vs 1-3%

4
Q

How is Chlamydia treated?

A

1 Doxycyclin 7 days - covers rectal infection too
CONTRA PREG

2 Azithromycin 1g once

3 Erythromycin 14 days

4 Ofloxacin 7 days but must be >18
CONTRA PREG

5 Amoxicillin 500 mg three times a day for seven days.

5
Q

What are complication of chlamydia infection?

A

Disseminated infection

  1. PID
  2. Lymphogranuloma venerum
    - Chlamydia trachomonis infects macrophages instead of epithelium resulting in trafficking to LN causing lymphadenopathy and disseminated infection

This will require 21 days treatment minimum with doxycylin

6
Q

How is recurrent herpes managed?

A

E.G >6 outbreaks of genital herpes in a year

Qualifies for suppressive therapy
12 months 400mcg aciclovir 400mg BD
- can reactivate post
>2 qualifies again for ongoing management

7
Q

How is ghonorrhoea treated?

A

pregnance Ceftriaxone IM and azithromycin

Penicillin