gynaecomastia Flashcards Preview

Endocrine AMK > gynaecomastia > Flashcards

Flashcards in gynaecomastia Deck (2)
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1

causes

physiological: normal in puberty
syndromes with androgen deficiency: Kallman's, Klinefelter's
testicular failure: e.g. mumps
liver disease
testicular cancer e.g. seminoma secreting hCG
ectopic tumour secretion
hyperthyroidism
haemodialysis
drugs: see below

2

A 22-year-old man presents to his general practitioner with enlarging breast tissue, which has been worsening over the last 3 months. He has also noticed a new lump on his left testicle. After a detailed history and examination, the general practitioner concludes that the man is likely to have testicular cancer.

starts with small lumps in males

What is the most likely diagnosis?

HCG secreting seminoma is a type of seminoma and is germ cell tumour. HCG secreting seminomas release human chorionic gonadotropin (HCG). This hormone can cause oestrogen production out of proportion with normal androgens, resulting in gynaecomastia.