HAART Flashcards

(36 cards)

1
Q

NRTI mechanism

A

Inhibit production of viral DNA from RNA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

NRTIs (nucleoside)

A

Abacavir
Emtricitabine
Lamivudine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

NRTIs (nucleotide)

A

Zidovudine

Tenofovir

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

NRTI AEs

A
Lactic acidosis (can be fatal)
Lipodystrophy
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

NNRTI mechanism

A

Inhibit production of viral DNA from RNA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

NNRTIs

A

Efavirenz
Etravirine
Rilpirvirine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

NNRTI AEs

A

Rash

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Protease inhibitor mechanism

A

Interfere w/ viral replication and cause production of nonfunctional viruses

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Protease inhibitors

A
-navir
Atazanavir
Darunavir
Fosamprenavir
Lopinavir
Ritonavir
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Integrase inhibitor mechanism

A

Blocks integration of viral genome into host genome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Integrase inhibitors

A

-gravir
Elvitegravir
Raltegravir

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

CCR5 antagonist

A

Prevents viral entry by blocking CCR5 coreceptor

Maraviroc

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Fusion inhibitor

A

Binds glycoprotein 41 blocking HIV virus fusion to CD4 cells

Envuvirtide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Antiretroviral w/ possibly fatal hypersensitivity rxn

A

Abacavir (NRTI)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Antiretroviral w/ BM suppression, anemia

A

Zidovudine (NRTI)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Antiretroviral w/ depression, vivid nightmares, teratogen

A

Efavirenz (NNRTI)

17
Q

Antiretroviral w/ hyperbilirubinemia, jaundice

18
Q

Protease inhibitor AEs

A

Hyperglycemia, DM, +TG

GI toxicity

19
Q

Antiretroviral that inhibits P450, “boosts” other drugs

A

Ritonavir boosts other protease inhibitors

20
Q

Abacavir

A

NRTI

AE: Possibly fatal hypersensitivity rxn

21
Q

Efavirenz

A

NNRTI

AE: teratogenic; depression, vivid nightmares

22
Q

Atazanavir

A

Protease inhibitor

AE: hyperbilirubinemia, jaundice

23
Q

Emtricitabine

24
Q

Elvitegravir

A

Integrase inhibitor

25
Etravirine
NNRTI
26
Darunavir
Protease inhibitor
27
Enfuvirtide
Fusion inhibitor
28
Fosamprenavir
Protease inhibitor
29
Lamivudine
NRTI
30
Rilpirvirine
NNRTI
31
Raltegravir
Integrase inhibitor
32
Tenofovir
NRTI
33
Maraviroc
CCR5 antagonist
34
Zidovudine
NRTI | AE: BM suppression, anemia
35
Lopinavir
Protease inhibitor
36
Ritonavir
Protease inhibitor (booster)