HAART Flashcards Preview

Medications > HAART > Flashcards

Flashcards in HAART Deck (36)
Loading flashcards...
1

NRTI mechanism

Inhibit production of viral DNA from RNA

2

NRTIs (nucleoside)

Abacavir
Emtricitabine
Lamivudine

3

NRTIs (nucleotide)

Zidovudine
Tenofovir

4

NRTI AEs

Lactic acidosis (can be fatal)
Lipodystrophy

5

NNRTI mechanism

Inhibit production of viral DNA from RNA

6

NNRTIs

Efavirenz
Etravirine
Rilpirvirine

7

NNRTI AEs

Rash

8

Protease inhibitor mechanism

Interfere w/ viral replication and cause production of nonfunctional viruses

9

Protease inhibitors

-navir
Atazanavir
Darunavir
Fosamprenavir
Lopinavir
Ritonavir

10

Integrase inhibitor mechanism

Blocks integration of viral genome into host genome

11

Integrase inhibitors

-gravir
Elvitegravir
Raltegravir

12

CCR5 antagonist

Prevents viral entry by blocking CCR5 coreceptor
Maraviroc

13

Fusion inhibitor

Binds glycoprotein 41 blocking HIV virus fusion to CD4 cells
Envuvirtide

14

Antiretroviral w/ possibly fatal hypersensitivity rxn

Abacavir (NRTI)

15

Antiretroviral w/ BM suppression, anemia

Zidovudine (NRTI)

16

Antiretroviral w/ depression, vivid nightmares, teratogen

Efavirenz (NNRTI)

17

Antiretroviral w/ hyperbilirubinemia, jaundice

Atazanavir

18

Protease inhibitor AEs

Hyperglycemia, DM, +TG
GI toxicity

19

Antiretroviral that inhibits P450, "boosts" other drugs

Ritonavir boosts other protease inhibitors

20

Abacavir

NRTI
AE: Possibly fatal hypersensitivity rxn

21

Efavirenz

NNRTI
AE: teratogenic; depression, vivid nightmares

22

Atazanavir

Protease inhibitor
AE: hyperbilirubinemia, jaundice

23

Emtricitabine

NRTI

24

Elvitegravir

Integrase inhibitor

25

Etravirine

NNRTI

26

Darunavir

Protease inhibitor

27

Enfuvirtide

Fusion inhibitor

28

Fosamprenavir

Protease inhibitor

29

Lamivudine

NRTI

30

Rilpirvirine

NNRTI