Haem

Question 1

Causes of severe thrombocytopenia

Answer 1

DIC
ITP
TTP
heamotologic malignancy

Question 2

Which anti TB medication lead to sideroblastic anemia

Answer 2

Isoniazid

Question 3

High leukocyte alkaline phosphate reaction

Answer 3

Leukamoid reaction

Question 4

How do you differentiate Leaukamoid reaction from CML

Answer 4

By raised LAP

Question 5

CLL common complication

Answer 5

Hypogammaglobulinemia

Question 6

JAK2 mutation positive in

Answer 6

Polycythemia rubra vera

Question 7

On bone marrow aspiration polycythemia vera shows

Answer 7

Panmyelosis and reduced iron stores

Question 8

Elevated Hb
Normal o2
Splenomegaly

Answer 8

Polycythemia Vera

Question 9

Normal neutrophil count

Answer 9

2-7.5

Question 10

Drugs causing neutropenia

Answer 10

Cytotoxics
Carbimazole
Clozapine

Question 11

Viral causes of neutropenia

Answer 11

Hepatitis
EBV
HIV

Question 12

Complication of tumor lysis syndrome

Answer 12

hyperkalaemia
hyperphosphataemia
hypocalcaemia
hyperuricaemia
acute renal failure

Question 13

Treatment for Burkitt lymphoma

Answer 13

Chemotherapy

Question 14

MOA of imatinib

Answer 14

Tyrosine kinase inhibitor

(Used in CML treatment)

Question 15

MOA of imatinib

Answer 15

Tyrosine kinase inhibitor

(Used in CML treatment)

Question 16

an increase in granulocytes at different stages of maturation +/- thrombocytosis
Abd discomfort
Splenomegaly

Answer 16

CML

Question 17

The combination of frequent infections, eczema and thrombocytopenia are characteristic of

Answer 17

Wiskot Aldrich syndrome

Question 18

Prophylactic medication for sickle cell disease

Answer 18

Hydroxyurea

Question 19

Tear drop cells seen in

Answer 19

Myelofibrosis

Question 20

Pencil poikilocytes seen in

Answer 20

Iron def anemia

Question 21

Schistocytes seen in

Answer 21

Intravascular hemolysis

Question 22

Reed sternberg cells

Answer 22

Hodgkin lymphoma

Question 23

Heinz bodies seen in

Answer 23

G6PD def

Question 24

gastrointestinal symptoms, combined with iron deficiency anaemia and highly positive anti-tissue transglutaminase (anti-TTG) antibodies, is strongly suggestive of a diagnosis of

Answer 24

Celiac disease

Question 25

Him paraproteinemia Raised ESR

Answer 25

Waldenstorm macroglonulinemia

Question 26

Raised reticulocytes Spherocytes Anemia

Answer 26

Hereditary spherocytosis

Question 27

Screening tool for hereditary angioedema

Answer 27

C4 levels

Question 28

Best test to diagnose for contact dermatitis

Answer 28

Skin patch test

Question 29

It's primarily used to diagnose allergies to foods, drugs, venom and some types of asthma

Answer 29

RAST test

Question 30

d for diagnosing immediate hypersensitivity reactions (Type I), such as food or respiratory allergies rather than delayed type hypersensitivity reactions (Type IV) like contact dermatitis

Answer 30

Skin prick test

Question 31

Abdominal, neurological and psychiatric complications

Answer 31

AIP

Question 32

Treatment for AIP

Answer 32

I/v heamatin

Question 33

Why rasburicase is given in chemo patients

Answer 33

To prevent tumor lysis syndrome

Question 34

MOA of cyclophosphamide

Answer 34

Cross linking DNA.

Question 35

Side effect of cyclophosphamide

Answer 35

Haemorrhagic cystitis

Question 36

Key investigation for CLL

Answer 36

Immunephenotyping

Question 37

Lymphocytic predominance in the presence of smudge cells.

Answer 37

CLL

Question 38

Most common complication of AML

Answer 38

DIC

Question 39

plethoric and cyanosed face with periorbital oedema, conjunctival injection, venous dilatation in the fundi, distended non-pulsatile neck veins and a positive Pemberton sign

Answer 39

SVC obstruction

Question 40

Basophilic stippling and clover leaf morphology

Answer 40

Lead poisoning