Rheumatology Flashcards
(88 cards)
1
Q
Classical finding of ankylosis spondylitis
A
Reduced lateral and forward flexion
2
Q
Radiological changes seen in ankylosis spondylitis in early stages
A
Sacroilitis
Syndesmophyte
3
Q
A
4
Q
Dermatological condition associated with antiphospholipid syndrome
A
Livedo reticularis
5
Q
Azathioprine causes which type of skin cancer
A
Basal cell carcinoma
6
Q
HLA B52 associated with
A
Takayasu arthritis
7
Q
What neurological condition associated with behcet syndrome
A
Aseptic meningitis
8
Q
Compression of median nerve
A
Carpal tunnel syndrome
9
Q
Compression of ulnar nerve
A
Cubital tunnel syndrome
10
Q
Common adverse effect of DENOSUMAB
A
Diarrhea
Dyspnea
11
Q
Anti Jo1 antibodies positive in
A
Dermatomyositis
Polymyositis
Pulmonary fibrosis
12
Q
Anti Mi2 antibody positive in
A
Dermatomyositis
13
Q
Investigation for Dermatomyositis
A
EMG
14
Q
Treatment of Dermatomyositis
A
Prednisolone
15
Q
Cutaneous manifestation of SLE
A
Discoid lupus erythromatosus
16
Q
Management of DLE
A
Topical steroid
Second line hydroxychloroquine
17
Q
Biopsy finding of DLE
A
Interface dermatitis
18
Q
Conditions causing scarring alopecia
A
DLE
Lichenplanus
Initial tinea capitus
Zinc def
Iron def
Carbimazole
19
Q
Schusters sign seen in
A
DLE
20
Q
Antibody associated with congenital heart block
A
Anti Ro (anti SSA)
21
Q
A
22
Q
Most common cause of iliopsoas abscess
A
Crohn disease
23
Q
Organism involved in iliopsoas abscess
A
S.aureus
24
Q
Muscles affected in DeQuervain tenosynovitis
A
Extensor pollicis brevis
Abductor pollicis longus
25
Muscles affected in carpal tunnel
Abductor pollicis brevis and opponens pollicis tendons
26
Vasculitis associated with Hep B
PAN
27
Vasculitis associated with hypertension
Takayasu
28
Hypertension with absent peripheral pulses
Takayasu
29
Vasculitis with renal impairment and respiratory symptoms
Eosinophilic granulomatosis with polyangiitis
30
arthritis, urethritis and conjunctivitis
Reactive arthritis
31
recurrent oral and genital ulceration
Behcet syndrome
32
recurrent polyserositis)
FMF
33
Characteristic feature of pseudogout
Chondrocalcinosis
34
Causes of pseudogout
Hyperparathyroidism
Hypothyroidism
Hemochromatosis
Low mag and phosphate
Wilson
Acromegaly
35
Antibodies positive in RA
Anti CCP antibodies
36
Oral a/e of doxy
Grey staining of teeth
37
Which treatment required before bisphosphonate treatment
Dental check up
38
Oral a/e of doxy
Grey staining of teeth
39
Bisphosphonale indication
OsteoporosisPajet's disease
40
'bull's eye maculopathy',
Typical of hydroxychloroquinone
41
retinopathy is with reduced colour differentiation, reduced central visual acuity, and floaters
Retinopathy due to hydroxychloroquinone
42
Antibody associated with systemic sclerosis
Anti centromere antibody
43
vomiting and retro-orbital pain, pulsatile tinnitus, and visual disturbance (most commonly peripheral visual fields). On ophthalmoscopy, you would expect to see papilloedema
Idiopathic intracranial hypertension
44
Anti scl 70 antibodies positive in
Diffuse cutaneous systemic sclerosis
45
Antibody positive in PBC
AMA
46
Long term glucocorticoid is risk factor for developing what condition
Osteoporosis
47
first-line drug treatment for patients at risk of fragility fractures
Bisphosphonates
48
Tendons involved in DeQuervain
Extensor policies brevis
Abductor policies longus
49
joint pain and swelling in conjunction with gastrointestinal symptoms
Enteropathic arthritis
50
Antibody positive in SLE
ANA
Anti ds DNA
51
Indication for sulfasalazine
Rheumatoid arthritis
IBD
52
Mainstay of ANCA associated Vasculitis is
Immunosuppressive therapy
53
CXR finding of ankylosing spondylitis
Apical fibrosis
54
Most common organism for septic arthritis
S.aureus
55
Treatment for septic arthritis
Fluxocallin
Clinda if penicillin allergy
56
Pain relieved by shaking hands
Carpal tunnel syndrome
57
What specific monitoring is recommended when considering starting hydroxychloroquinone
Visual acuity and fundoscopy
58
Cells affected in osteopetrosis
Osteoclasts
59
First line treatment for knee osteoarthritis
Topical diclo
60
Sensory loss of posterolateral aspect of leg and lateral aspect of foot, weakness in plantar flexion of foot, reduced ankle reflex, positive sciatic nerve stretch test
Nerve root affected
S1.nerve lesion
61
sensory loss over the anterior of the thigh, weakness of knee extension and a reduced patella reflex
Nerve root.
L3
62
sensory loss over the knee, weakness of ankle dorsiflexion and a reduced patella reflex
L4
63
nerve root compression would present differently with sensory loss in the dorsum of the foot alongside weakness of big toe extension,
L5
64
sensory loss in the posteromedial aspect of the leg, buttocks and genitals and weakness in knee flexion
Nerve affected
S2
65
RANK ligand inhibitor
Denosumab
66
Anti-smooth muscle antibodies are associated with
Autoimmune hepatitis
67
Defect in elastin
Williams syndrome
68
Treatment for methotrexate toxicity
Folinic acid
69
70
Treatment of pagets
bisphosphonate (either oral risedronate or IV zoledronate
71
Fever/back pain with pain on extension of the hip
Iliopsoas abscess
72
Anti rheumatic drug safe to use in pregnancy
Sulfasalazine
73
Neonatal complications of SLE
Congenital heart block
74
Radial tunnel syndrome affects what nerve
Post interosseus nerve
75
A ______ may be needed to look for individuals prone to azathioprine toxicity
TPMT
76
Main side effect of colchicine
Diarrhea
77
chronic, activity-related hand pain and stiffness affecting the DIP and CMC joints, which is characteristic of
Hand osteoarthritis
78
Wedge-shaped discs are more indicative of
Osteoporosis and vertebral compression fractures
79
'Rugger-Jersey' spine seen in
Hyperparathyroidism
80
Most common organism for osteomyelitis
S.aureus
81
Follicular keratin plugs
DLE
82
MOA of mycophenolate mofetil
Inhibits inspire 5 monophosphate dehydrogenase needed for purine synthesis
83
84
Mechanism of McArdle disease
This is an autosomal recessive type V glycogen storage disease caused by myophosphorylase deficiency. This leads to an inability to effectively break down glycogen into glucose-1-phosphate during periods of exercise
85
How do you monitor activity of AIHA
he disease activity is typically monitored using other parameters such as reticulocyte count, lactate dehydrogenase levels, haptoglobin levels, and direct Coombs test rather than ANCA testing
86
Antibodies positive in APLS
Anti cardio lipid antibody
Lupus anticoagulant
Anti beta 2 glycoprotein
87
Ophthalmology complication associated with with temporal arteritis
Anterior ischemic optic neuropathy
88
Treatment of choice in SLE that is given long term
Hydroxychloroquinone
