Flashcards in Haldane's Rule Deck (5):
three requirements for haldane's rule to apply
x linked recessive
reduced fitness (genetic lethal)
-negative relevant family history
what are excluded?
x linked diseases caused by dynamic mutations, such as fragile x
what does haldane's rule explain?
why not all mothers of x-linked recessive disorder sons are carriers themselves
DMD where fitness = 0