Causes of a loud S2
hypertension: systemic (loud A2) or pulmonary (loud P2)
hyperdynamic states
atrial septal defect without pulmonary hypertension
Causes of a soft S2
Aortic stenosis
Causes of a fixed split S2
Atrial septal defect
Causes of a widely split S2
deep inspiration
RBBB
pulmonary stenosis
severe mitral regurgitation
Causes of a REVERSED split S2- P2 occurs before A2
LBBB severe aortic stenosis right ventricular pacing WPW type B (causes early P2) patent ductus arteriosus