HELICOBACTER PYLORI Flashcards

1
Q

caracteristicas microbiologicas

A
  • bacilos ESPIRALES gram -
  • moviles: flagelos polares
  • LPS poco antigenico
  • COLONIZAN CRONICAMENTE EL ESTOMAGO
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2
Q

mecanismo

A
  1. bloquean produccion de acido gastrico + neutrolizacion (UREASA)
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3
Q

reservorio

A

humano

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4
Q

UREASA

A
  1. bacteria atraviesa barrera de moco
  2. libera la UREASA (esta media la reaccion quimica que la convierte en amonio)
  3. crean microambiente
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5
Q

factor de risgo y protector

A
  • FR: gastritits, ulceras gastricas, adenoCa gastrico y linfomas tipo MALT
  • FP: RGE y AdenoCa esofagico

ulceras gastricas 85%
ulceras duodenales 95%

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6
Q

DX

A
  • prueba de ureasa: en biopsia o aliento. CARBONOS MARCADOS PARA DETECTAR LA BACTERIA
  • microscopia gastrica
  • cultivo dificil
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7
Q

TX

A
  • solo en px sintomaticos
  • combinacion de amoxicilina + claritromicina + IBP
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