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Flashcards in Hematology Deck (11):
1

Anemias resulting from increased destruction of RBC

1. Sickle cell disease
2. Glucose - 6 - Phosphate Dehydrogenase Anemia

2

Sickle cell disease

genetic; chronic anemia, pain, disability, organ damage, increased risk for infection, early death.
TX: hydration, oxygen ( lack cause sickling ), transfusion with RBC to elevate HbA

3

Glucose - 6 - Phosphate Dehydrogenase Anemia

hemolytic anemia (blood cell destroying)
TX: Hydration - to prevent debris and hemoglobin from collecting in kidney tubules - ARF ( Mannitol); transfusions.

4

Anemias resulting from decreased production of RBC

1. Iron deficiency anemia
2. Vitamin B12 deficiency anemia
3. Folic acid deficiency anemia
4. Aplastic anemia

5

Iron deficiency anemia (microcytic)

2/3 of iron - in hemoglobin; 1/3 - bone marrow, spleen, liver, muscle. Serum ferritin < 10 ng/ml (normal 12-300 ng/ml)
TX: iron reach food; Ferrous Sulfate ( oral supplement , take between meals); severe - iron solution IM ( z track)

6

Iron Food Sources

red meat, organ meat, egg yolks, kidney beans, leafy green vegetables, raisins

7

Vitamin B12 deficiency anemia (macrocytic)

B12 activate enzyme that move folic acid into cell when DNA synthesis occurs + nerve function ;

8

Vitamin B12 Food Sources

animal proteins, eggs, nuts, dairy products, dried beans, citrus fruit, leafy green vegetables.

9

Folic acid deficiency anemia: food sources

green leafy vegetables, liver, yeast, citrus fruit, dried beans, nuts.

10

Aplastic anemia

deficiency of RBC because of failure of the bone marrow to produce this cells; usually occurs with leukopenia, thrombocytopenia.

11

Pancytopenia

reduction in the number of red, white blood cells + platelets.