Flashcards in Hematology Deck (11):
Anemias resulting from increased destruction of RBC
1. Sickle cell disease
2. Glucose - 6 - Phosphate Dehydrogenase Anemia
Sickle cell disease
genetic; chronic anemia, pain, disability, organ damage, increased risk for infection, early death.
TX: hydration, oxygen ( lack cause sickling ), transfusion with RBC to elevate HbA
Glucose - 6 - Phosphate Dehydrogenase Anemia
hemolytic anemia (blood cell destroying)
TX: Hydration - to prevent debris and hemoglobin from collecting in kidney tubules - ARF ( Mannitol); transfusions.
Anemias resulting from decreased production of RBC
1. Iron deficiency anemia
2. Vitamin B12 deficiency anemia
3. Folic acid deficiency anemia
4. Aplastic anemia
Iron deficiency anemia (microcytic)
2/3 of iron - in hemoglobin; 1/3 - bone marrow, spleen, liver, muscle. Serum ferritin < 10 ng/ml (normal 12-300 ng/ml)
TX: iron reach food; Ferrous Sulfate ( oral supplement , take between meals); severe - iron solution IM ( z track)
Iron Food Sources
red meat, organ meat, egg yolks, kidney beans, leafy green vegetables, raisins
Vitamin B12 deficiency anemia (macrocytic)
B12 activate enzyme that move folic acid into cell when DNA synthesis occurs + nerve function ;
Vitamin B12 Food Sources
animal proteins, eggs, nuts, dairy products, dried beans, citrus fruit, leafy green vegetables.
Folic acid deficiency anemia: food sources
green leafy vegetables, liver, yeast, citrus fruit, dried beans, nuts.
deficiency of RBC because of failure of the bone marrow to produce this cells; usually occurs with leukopenia, thrombocytopenia.