Heme and Immune System Diseases

Question 1

Blood is the only

Answer 1

liquid connective tissue

Question 2

Functions of blood

Answer 2

Temp. regulation,pH balance, nutritional hormone transport, waste disposal, immune response

Question 3

RBC are removed from circulation via

Answer 3

the spleen

Question 4

What is anemia

Answer 4

an absolute decrease in the red cell mass as measured by RBC count, hemoglobin concentration, and PCV

Question 5

3 major rule-outs for anemia

Answer 5

-loss, lysis, lack of production

Question 6

Anemias are

Answer 6

Regenerative or Non-regenerative

Question 7

In regenerative anemia, the bone marrow responds to the

Answer 7

decreased red cell mass by increasing RBC production and releasing reticulocytes

Question 8

In non regenerative anemia, the bone marrow responds

Answer 8

Inadequately to the increased need for RBC

Question 9

A reticulocyte is

Answer 9

an immune stage of a red blood cell

Question 10

Diagnosis of anemia

Answer 10

CBC, Blood smear, HX

Question 11

Clinical signs associated with anemia

Answer 11

pale MM, +/- jaundice, weakness, tachycardia, depression, dehydration, hypovolemia, shock

Question 12

Hemorrhage

Answer 12

typically results after trauma, may be associated with severe thrombocytopenia

Question 13

Treating a hemorrhage

Answer 13

ID the cause and treat accordingly, treat shock and volume replacement, transfusions

Question 14

Iron deficiency anemia occurs after

Answer 14

chronic blood loss, sever flea infestation, internal parasite infestation

Question 15

Etiology of Hemolysis in dogs and cats

Answer 15

Idiopathic IMHA, infectious, neoplastic

Question 16

Etiology of hemolysis in horses

Answer 16

Neonatal Isoerythrolysis

Question 17

Blood-borne parasites may cause

Answer 17

hemolytic anemia

Question 18

Mycoplasma hemofelis

Answer 18

Bacteria that is the common cause of hemolytic anemia in cats

Question 19

Transmission of Mycoplasma hemofelis

Answer 19

Fleas; direct transmission associated with fighting suspected in cats

Question 20

Cytauxzoon felis

Answer 20

protozoal organism transmitted to domestic cats by tick bites. causes fatal anemia in cats (within days)

Question 21

Babes canis, Babesia gibsoni

Answer 21

Tick-borne disease in dogs (Rhipicephalus sanguineus)

Question 22

What are Heinz bodies?

Answer 22

Denaturation of hemoglobin that occurs secondary to oxidative damage

Question 23

Toxin-induced anemia aka

Answer 23

Heinz body anemia

Question 24

Breed disposition of IMHA

Answer 24

poodles, old English sheep dogs, Irish settlers, cocker spaniels

Question 25

Diagnosis of IMHA

Answer 25

Agglutination test (in house), Coombs test (dx lab)

Question 26

Treatment of IMHA

Answer 26

Immunosuppressants, Anti-ulcer therapy, Tx for DIC if necessary

Question 27

Client education for IMHA

Answer 27

Guarded prognosis, 30-40% mortality rate, relapses common

Question 28

Origin of Platelets

Answer 28

Bone marrow

Question 29

Function of platelets

Answer 29

blood clotting

Question 30

Increased platelets is called

Answer 30

Thrombocytosis

Question 31

Decreased platelets called

Answer 31

Thrombocytopenia

Question 32

Toxin that affects platelets of small animals

Answer 32

Rodenticide

Question 33

IMTP diagnosis

Answer 33

CBC/blood smear, Clinical signs: petechial hemorrhages

Question 34

Treatment of IMTP

Answer 34

Immunosuppressants, Chemotherapy, Platelet rich plasma transfusion, anti-ulcer drugs

Question 35

Von Willbrand's disease (vWD)

Answer 35

a blood disease caused by a deficiency of von Willebrand Factor (vWF), an adhesive glycoprotein in the blood required for normal platelet binding

Question 36

Most common hereditary blood clotting disorder in dogs

Answer 36

vWD

Question 37

Clinical signs of vWD

Answer 37

prolonged bleeding after sx or estrus, nose bleeds, petechiae

Question 38

Leukocytes (WBC) origin and function

Answer 38

Bone marrow; inflammatory response

Question 39

Lymphoma

Answer 39

in animals, a type of cancer defined by proliferation of malignant lymphocytes within solid organs such as the lymph nodes, bone marrow, liver, and spleen

Question 40

Lymphomas are defined by

Answer 40

Anatomic location: Mediastinal, Alimentary, Multicentric. Extent of disease

Question 41

Feline lymphoma, 70% of cases associated with

Answer 41

FeLV, most commonly multi centric lymphoma

Question 42

Feline Lymphoma clinical signs

Answer 42

Peripheral lymphadenopathy, anorexia, V+, Dyspnea, weight loss

Question 43

Diagnosis of Feline lymphoma

Answer 43

FNA with cytology

Question 44

Client education for feline lymphoma

Answer 44

No cure, Px: 2-42 months, Chemo side effects

Question 45

Most common hematopoietic tumor in dogs

Answer 45

Canine lymphoma