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Flashcards in histology 2- cartilage Deck (42)
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1

origin of chondroblast

mesenchyme cells

2

cartilage composition

cells and ECM

3

cartilage

composition
perichondrium
avascular

4

cartilage cells

chondroblast
chondocytes

5

chondroblast

on outside surface of tissue, produce ECM, not completely surrounded by ECM yet

6

chondrocytes

also produce matrix, also maintain it. on inside of cartilage, completely surrounded by ECM

7

when do chondroblast turn into chondrocytes

when ECM completely surrounds the cell

8

what is space called that cells sit inside after surrounded by ECM

lacunae

9

characteristics of cartilage ECM

1. 95% water
2. Rich in GAG's and proteoglycans
3. allows for withstanding forces, resilent

10

dense CT covering most cartilage

perichondrium

11

perichondrium

contains blood vessels, nerves, chondrogenic cells, type 1 cartilage, important in growth and maintenance of cartilage

12

chondrogenic cells

found in perichondrium, produce chondroblast

13

what limits diffusion thus limiting growth in cartilage

avascular

14

2 mechanisms of growth

appositional growth
interstital growth

15

appositional growth

growth by additional to existing surface. generation of new chondroblast, adding in addiontal ECM

16

interstital growth

growth by internal expansion. proliferation of chondrocytes and formation of isogenous groups. have to start producing ECM in between cells which makes tissue grow

17

isogenous groups

cluster of chondrocytes in lacunae, undergo mitosis

18

3 types of cartilage

1. hyalin
2. elastic
3. fibrocartilage

19

hyalin cartilage ECM composition

75% water, proteoglycans, Hyaluaric acid, type 2 collagen!

20

what is most common cartilage in human body

hyalin cartilage

21

location of hyalin cartilage

nose, larynx, tracheal cartialge, fetal bone models, articular surfaces

22

does hyalin have perichondrium

yes

23

appearance of hyalin cartilage

fresh discect- bluish-white and translucent
matrix is basophilic- can't see collagen type 2 fibers

24

shape of chondrocytes compared to chondroblast

cytes are more rounded.

25

hyalin cartilage is more ____philic

basophilic

26

perichondrium is more _____philic

eosinphilic

27

what indicates growing cartilage, newly synthesized cells

isogenous groups

28

right around isogenous groups stain _____

darker

29

what is stained lighter around isogenous groups, darker?

interterritorial matrix, territorial matrix.

30

interterritorial matrix has lots of ______

collagen fibers