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Flashcards in histology 3- bone Deck (63)
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1

functions of bone

protection
support
mechanical basis for movement
storage
blood cell formation

2

blood cell formation happens where and is called what

in red bone marrow. hematopoiesis

3

storage function of bone

stores minerals. calcium, phosphate. yellow marrow store triglycerides.

4

classification of bone

long
short
flat
irregular
seasmoid

5

long bone location

femur, shaft portions and 2 ends, longer than wide.

6

short bone location

carpal and tarsal bones in wrist and ankles.

7

flat bone locatoin

very thin, plate like. sternum, ribs, scapula, skull bones

8

irregular bone locatoin

very complicated shape. pelvis, vertebrae

9

sesamoid bone locatoin

almost cube shape, very specific. form in tendon. largest is patella.

10

gross observation of bone tissue

compact
spongy- has trabeculae

11

long bone structure

epiphysis
metaphysis
diaphysis of shaft.

12

epiphysis

on ends of long bone. compact bone on outside, spongy bone on inside- spicules look random but are very particular.

13

during growth the epiphysis and metaphysis are separated by what

growth plate. (epiphyseal plate).

14

in adults, radiographs identify growth plate as what

epiphyseal line.

15

epiphyseal plate is responsible for what

lengthening of the long bone.

16

epiphyseal plate is made of what and is replaced by what after puberty

hyalin cartilage. replaced with bone. bone is done growing.

17

diaphysis

compact bone on outside, marrow on inside.
contains red/yellow marrow. as we age red turns to yellow marrow

18

periosteum

-covers outer surface of bone
-where muscle/tendon/ligament attaches
-vascularized
-contains osteoprogenitor cells.

19

2 layers of periosteum

outer fiber layer- dense connective tissue
inner osteogenic (cellular) layer.

20

endosteum

lines marrow cavity.
consists of cells that belong to the stroma of the marrow or are derived from resting osteoblast

21

sharpys fibers

connect periosteum to bone. transfers force from muscle contraction.

22

short, flat, sesamoid, irregular bone structure

(layers) compact bone, dipole (spongy), compact bone.

23

bone composition (2)

cells
extracellular matrix (ECM)

24

cells of bone

osteogenic cell- mesenchymal kind of cells
osteoblast- make osteocytes
osteocyte
osteoclast- very large

25

ECM of bone

organic- osteoid
inorganic- hydroxyapatite crystals

26

ECM- osteoid contains what

- type one collagen fibers
- bone matrix proteins (BMP)
- glycoproteins
- osteocalsin
-osteonectin

27

what lays down layer of osteoid

osteoblast

28

what do BMP's contain

GAG's

29

what is osteocalsin

- vitamin K dependent polypeptide.
- produced by osteoblast
- important in promoting calcification of matrix giving us inorganic portion

30

what helps give bones its inorganic (HA) portion.

osteocalsin