Flashcards in histology 3- bone Deck (63)
functions of bone
mechanical basis for movement
blood cell formation
blood cell formation happens where and is called what
in red bone marrow. hematopoiesis
storage function of bone
stores minerals. calcium, phosphate. yellow marrow store triglycerides.
classification of bone
long bone location
femur, shaft portions and 2 ends, longer than wide.
short bone location
carpal and tarsal bones in wrist and ankles.
flat bone locatoin
very thin, plate like. sternum, ribs, scapula, skull bones
irregular bone locatoin
very complicated shape. pelvis, vertebrae
sesamoid bone locatoin
almost cube shape, very specific. form in tendon. largest is patella.
gross observation of bone tissue
spongy- has trabeculae
long bone structure
diaphysis of shaft.
on ends of long bone. compact bone on outside, spongy bone on inside- spicules look random but are very particular.
during growth the epiphysis and metaphysis are separated by what
growth plate. (epiphyseal plate).
in adults, radiographs identify growth plate as what
epiphyseal plate is responsible for what
lengthening of the long bone.
epiphyseal plate is made of what and is replaced by what after puberty
hyalin cartilage. replaced with bone. bone is done growing.
compact bone on outside, marrow on inside.
contains red/yellow marrow. as we age red turns to yellow marrow
-covers outer surface of bone
-where muscle/tendon/ligament attaches
-contains osteoprogenitor cells.
2 layers of periosteum
outer fiber layer- dense connective tissue
inner osteogenic (cellular) layer.
lines marrow cavity.
consists of cells that belong to the stroma of the marrow or are derived from resting osteoblast
connect periosteum to bone. transfers force from muscle contraction.
short, flat, sesamoid, irregular bone structure
(layers) compact bone, dipole (spongy), compact bone.
bone composition (2)
extracellular matrix (ECM)
cells of bone
osteogenic cell- mesenchymal kind of cells
osteoblast- make osteocytes
osteoclast- very large
ECM of bone
inorganic- hydroxyapatite crystals
ECM- osteoid contains what
- type one collagen fibers
- bone matrix proteins (BMP)
what lays down layer of osteoid
what do BMP's contain
what is osteocalsin
- vitamin K dependent polypeptide.
- produced by osteoblast
- important in promoting calcification of matrix giving us inorganic portion