Histology of the endometrium Flashcards Preview

Semester 4 - Reproductive System > Histology of the endometrium > Flashcards

Flashcards in Histology of the endometrium Deck (18)
1

What are the three layers of the uterus?

Endometrium

Myometrium

Perimetrium

2

What are the histological layers of the endometrium?

Simple columnar on surface

Large lamina propria

3

What does the lamina propria of the endometrium contain?

Stroma and glands

4

How many smooth muscle layers in myometrium?

4

5

What two layers is the endometrium broken down into?

Stratum functionalis

Stratum basalis

6

What are the two layers of the S.functionalis?

Outer compact layer

Deeper spongy layer

7

What are the three phases of endometrium?

Proliferative

Secretory 

Menstrual

8

What is the blood supply of the uterus? 

Uterine artery (mainly), small contribution from ovarian artery

9

What phase is this? 

Proliferative

10

What hormone is proliferative phase under control of? 

Outline three things that occur in proliferative phase

Increase depth of S.functionalis, regenerates form cells lining glands of S basalis

Cells around developing glands, stromal cells, proliferate

Increased length of endometrial glands (Straight, unbranched)

11

What is the blood supply of S.basalis

Straight arteries

12

What is the blood supply s.funcitonalis?

Spiral arteries

13

What phase is this? 

Secretory phase

14

What occurs in secretory phase? What hormon responsible?

Progesterone

Galnds grow more than surrounding lamina propria and become coiled. Secrete glycogen.

Stroma becomes oedematous and stromal cells undergo decidulisation

15

What is decidualization? 

Changes including 

- Increased glandular epithelial secretion

- Glycogen accumulation in stromal cells

- Promotes spiral arteriole development

- Promotes oedema 

16

What phase is this? 

Menstrual phase

17

What hormonal changes happen in menstrual phase? Name three changes

Decrease progesterone 

- Corpus luteum regresses (absence of HCG) leading to spasm of spiral arteries due to decreased prostaglandin 

- S.functionalis deprived of nutrients, undergoes necrosis

- Straight arteries do not spasm, stratum basalis remains

18

What hormone do decidual cells secrete?

Prolactin