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"People can acquire immunity"

Thucydides (430 BC)

1

Time and place where smallpox became endemic

10th century China

2

Process that involves exposing healthy people to material from the lesion caused by the disease, either by putting it under the skin or inserting powdered scabs into the nose

Variolation

3

Wife of British ambassador; performed variolation technique on her son to save him from smallpox

Lady Mary Wortley Montague

4

Developed the first vaccine for smallpox

Edward Jenner

5

Discovered lymphoid tissue in the small intestine

Peyer

6

Name of the boy tested in Edward Jenner's experiment

James Phipps

7

Discovered phagocytosis

Ernst Haeckel

8

Father of Immunology

Louis Pasteur

9

Proposed the Humoral Theory of Immunity

Emil Von Behring and Shibasaburo Kitasata

10

"Chicken cholera bacillus" and attenuated vaccine

Louis Pasteur

11

Demonstration of cutaneous (delayed-type) hypersensitivity

Robert Koch

12

Cellular theory of immunity through phagocytosis

Elie Metchnikoff

13

"Father of Humoral Immunity"
"Side Chain Receptor Theory"
"Antibody formation theory"

Paul Ehrlich

14

Immediate hypersensitivity anaphylaxis

Paul Portier & Charles Richet

15

Arthur's reaction of intermediate hypersensitivity

Maurice Arthus

16

Antigen-antibody binding hypothesis

John marrack

17

Development of polio vaccine

Salk & Sabin

18

Development of vaccine against yellow fever

Reed

19

Discovered the complement

Jules Bordet

20

Discovered the Major Histocompatibility Complex (MHC)

John Doucet

21

Immune genetics of MHC

Baruj Banascraf

22

Clonal Selection Theory
Identification of antibody molecule
Interferon
Human Leukocyte Antigen (HLA)
Immunological tolerance hypothesis

Macfarlane Burnet

W/ frank fenner for ITH

23

T cell restriction to MHC

Rolf Zinckernagel & Peter Doherty

24

First monoclonal antibodies (w/)
Identification of genes for T cell receptor
Monoclonal Hepatitis B vaccines

George Köhler (w/ Cesar Milstein)

25

Th1 vs. Th2 model of T helper cell function

Identification of toll-like receptor
FOXP3

Timothy Mosmann

26

Development of papillomavirus vaccine

Ian Frazer

27

Hemolytic Plaque Assay

Neil Jurne

28

Immunologic Tolerance
Investigated problem to graft rejection

Peter Medawar