HIV/AIDs

Question 1

What is HIV

Answer 1

A retrovirus containing RNA that converts to DNA and inserted into the host genome by reverse transcriptase

Question 2

What does HIV bind to with the help of CCR5?

Answer 2

CD4 via gp120

Question 3

What happens after HIV binds to CD4+ T cell?

Answer 3

Loss of cells expressing CD4+ T cell

• Massive viral replication

Question 4

What happens to the patient during the first stage of HIV infection?

Answer 4

Flu like symptoms

• Asymptomatic

Question 5

What cell clears the HIV to allow CD4+ T cells to recover?

Answer 5

CD8+ T cells

Question 6

What is seroconversion?

Answer 6

Antibodies become apparent in the blood

Question 7

How does HIV become AIDs?

Answer 7

When there is less than 20% of CD4+ in the body

Question 8

What are the symptoms of AIDs?

Answer 8

• Oral thrush (Candidiasis)
• Tuberculosis
• Shingles
• Failure of T cell memory

Question 9

What is Kaposi’s Sarcoma?

Answer 9

Complication of AIDs

Question 10

How is Kaposi’s Sarcoma caused?

Answer 10

Immunodepletion from HIV

Question 11

What virus causes Kaposi’s Sarcoma?

Answer 11

Human Herpesvirus 8

Question 12

What is the HIV latency period?

Answer 12

Slow decline in CD4+ T cells numbers to a threshold point

Question 13

What is the treatment to HIV?

Answer 13

Human Antiretroviral

Vaccines