HIV + AIDS

Question 1

pathology of HIV?

Answer 1

binds to CD4+ receptors travels to lymphoid tissue virus replicates and disseminates

Question 2

who is at risk of HIV?

Answer 2

PWID blood transfusion condomless sex MSM needle stick injury

Question 3

when does onset of primary infection usually occur?

Answer 3

2-4 wks after exposure

Question 4

when is most infective period of infection?

Answer 4

primary infection (2-4wks after exposure)

Question 5

features of primary infection?

Answer 5

fever wt loss maculopapular rash myalgia pharyngitis headache aseptic meningitis

Question 6

features of asymp HIV infection?

Answer 6

diarrhoea fatigue ulcers parotitis candidiasis psoriasis sebhorroeic dermatitis lymphadenopathy

Question 7

first line HIV Ix?

Answer 7

serum HIV ELISA (window of 3wks, so may need to retest)

Question 8

what can be given before HIV exposure?

Answer 8

PreP

Question 9

what can be given after HIV exposure? what else does it protect against?

Answer 9

PEPSE Hep B

Question 10

what is slim’s disease?

Answer 10

HIV assoc wasting

Question 11

what pneumonia do HIV patients often get?

Answer 11

pneumocystis jiroveci

Question 12

what skin infections do HIV pts often get?

Answer 12

HZV HSV HPV candidiasis

Question 13

what Tx is given for pneumocysti jiroveci pneumonia?

Answer 13

co trimoxazole and steroids

Question 14

what eye condition do HIV pts often get?

Answer 14

CMV retinitis

Question 15

what virus reactivation causes PML?

Answer 15

JC virus

Question 16

what protozoa can cause cerebral abscesses in HIV pts?

Answer 16

toxoplasma gondii

Question 17

how long, usually, does it take for HIV to become AIDS?

Answer 17

6-9yrs

Question 18

features of kaposi’s sarcoma? what causes it?

Answer 18

purple papule HSV 8

Question 19

features of NHL? what causes it?

Answer 19

wt loss, abdo pain, diarrhoea EBV

Question 20

what is Tx for HIV?

Answer 20

HAART (combination of 3 drugs)

Question 21

label

Answer 21