Hormones and functions

Question 0

Serotonin

Answer 0

Site of production: stomach mucosa
Target: stomach
Activity: causes contraction of stomach muscle

Question 1

Gastrin

Answer 1

Site of production: stomach mucosa
Target organ: stomach
Activity: causes gastric glands to increase secretory activity; most pronounced effect is on HCl secretion

Question 2

Somatostatin

Answer 2

Production: stomach mucosa
Target: stomach
Activity: inhibits gastric secretion of all products; inhibits gastric motility and emptying

Target: pancreas
Activity: inhibits secretion

Target: small intestine
Activity: inhibits GI blood flow; thus inhibits intestinal absorption

Question 3

Intestinal gastrin

Answer 3

Production: duodenal mucosa
Target: stomach
Activity: stimulates gastric glands

Question 4

Secretin

Answer 4

Production: duodenal mucosa
Target: stomach
Activity: inhibits gastric gland secretion during gastric phase of secretion

Target: pancreas
Activity: increases output of pancreatic juice rich in bicarbonate ion

Target: liver
Activity: increase bile output

Question 5

Cholecystokinin

Answer 5

Production: duodenal mucosa
Target: stomach
Activity: inhibits gastric gland secretion during gastric phase of secretory activity

Target: pancreas
Activity: increases output of enzyme-rich pancreatic juice

Target: gallbladder
Activity: stimulates organ to contract and expel stored bile

Target: sphincter of oddi
Activity: relaxes to allow entry of bile and pancreatic juice into duodenum

Question 6

Gastric inhibitory peptide (GIP)

Answer 6

Production: duodenal mucosa
Target: stomach
Activity: inhibits gastric gland secretion during gastric phase

Question 7

Enterogastrone

Answer 7

Production: duodenal mucosa
Target: stomach
Activity: inhibits motility of stomach smooth muscle