IDS Flashcards

1
Q

Cells seen in measles

A

Warthin-Finkeldy (multinucleated giant cells), and also Koplik spots (opposite 2nd upper molars at exit of Stensen’s duct)

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2
Q

Herpes simplex

A

Cowdry Type A (pink to purple intranuclear inclusions)

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3
Q

Varicella zoster (chickenpox)

A

Dewdrops on a rose petal

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4
Q

CMV

A

Owl’s eye (intranuclear basophilic inclusions surrounded by clear halo)

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5
Q

EBV

A

Mononucleosis, burkitt’s lymphoma, nasophrayngeal CA, B-cell non-Hodgkin’s lymphoma

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6
Q

Heterophile (Monospot) negative

A

CMV

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7
Q

Heterophile (monospot) positive

A

EBV

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8
Q

Pseudomembrane

A

Diphtheria

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9
Q

Granulomatosis infantiseptica

A

Listeria monocytogenes (gram positive intracellular bacteria)

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10
Q

Capsule of Bacillus anthracis

A

Only non-polysaccharide capsule, composed of D-glutamate peptides

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11
Q

Fleur-de-lis pattern of necrotizing pneumonia (pale necrotic center with red, hemorrhagic periphery)

A

Pseudomonas

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12
Q

Perivascular blue haze

A

Pseudomonas

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13
Q

Buboes

A

Yersinia pestis

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14
Q

Organism causing chancroid

A

Haemophilus ducreyi

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15
Q

Organism causing granuloma inguinale

A

Klebsiella granulomatis

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16
Q

Painful, prominent, non-indurated buboes

A

Haemophilus ducreyi (chancroid)

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17
Q

Beefy red ulcer with indurated borders

A

Klebsiella granulomatis (granuloma inguinale)

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18
Q

Gram negative coccobacilli

A

BOTH chancroid and granuloma inguinale)

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19
Q

Donovan bodies

A

Granuloma inguinale (may dove sa aking groin / inguinal area)

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20
Q

Produced by APCs for TH1 differentiation

A

IL 12

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21
Q

Produced by TH1 to activate macrophages

A

IFN-gamma

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22
Q

Cytotoxic T-cells

A

MHC I, CD8, Th2

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23
Q

Helper T cells

A

MHC II, CD4, Th1 and Th17

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24
Q

Focus of caseation necrosis in TB?

A

Ghon focus

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25
Ghon focus + lymph nodes
Ghon complex
26
Healed Ghon focus leading to fibrosis and/or calcification
Ranke complex
27
Secondary or reinfection of TB, tends to be cavitary
Simmon focus
28
Most common form of extrapulmonary TB
TB adenitis (scrofula)
29
Most commonly affected segment in GITB
Ileum
30
Disseminated intracellular infection in ICC individuals (ex AIDS)
Mycobacterium avium intracellulare complex (MAC)
31
Two types of leprosy
Paucibacillary/tuberculoid and multibacillary/lepromatous
32
Lipid laden macrophages seen in lepromatous leprosy
Lepra cells (macrophages) with globi (AFB)
33
Lesion of primary syphilis
Chancre
34
Causative agent of syphilis
Treponema pallidum
35
Manifestation of secondary syphilis
Oral cavity ulcer, palms and soles
36
Lesion of tertiary syphilis
Gumma
37
Other complications of tertiary syphilis
Neurosyphilis, aortitis (obliterative endarteritis of the vasa vasorum, causing aneurysm)
38
Manifestations of congenital syphilis
Saber shins and saddle nose, interstitial pneumonia, triad of late manifestations - interstitial keratitis / Hutchinson teeth / CN VIII deafness
39
Toxin of C. perfringens
Alpha toxin (lecithinase)
40
Causative agent of gas gangrene
C. perfringens
41
Causative agent of pseudomembranous colitis
C. difficile
42
Two toxins of C. difficile
Toxin A: chemokine, toxin B: cytotoxin
43
Most common bacterial STI
Chlamydia trachomatis
44
Seen in chlamydia urethritis
Purulent discharge WITHOUT ORGANISMS
45
Caused by Chlamydia L strains
Lymphogranuloma venereum
46
Structure stained by India ink in Cryptococcus neoformans
Polysaccharide capsule
47
Structure seen in candida albicans
Pseudohyphae
48
Characteristic of Aspergillus morphology
Septate hyphae that branch at acute angles (A-A, acute aspergillus)
49
Characteristic of Mucor morphology
Septate hyphae that branch at right angles
50
Mold with CNS involvement (rhinocerebral)
Aspergillus
51
Causative organism of babesiosis
Babesia microti, Babesia divergens
52
Causative organism of malaria
Plasmodium
53
Used for diagnosis of malaria and babesiosis on blood smear
Giemsa stain
54
Maltese cross pattern
Babesia
55
Asexual stages of parasite with hemozoin
Malaria
56
Parasite without hemozin
Babesia
57
Special lesion of cerebral malaria
Durck granuloma
58
Four kinds of leishmaniasis
Visceral (splenic, liver, LN), cutaneous, mucocutaneous, diffuse cutaneous
59
General morphology of leishmaniasis
Macrophages filled with leishmania
60
Hyperpigmentation seen in leishmaniasis
Kala-azar
61
African sleeping sickness
Trypanosoma brucei
62
Complications of T. cruzi
Dilated cardiomyopathy, megacolon and megaesophagus Tom Cruise gave me a reduviid bug in South America. It broke my HEART, kaya Chagas siya
63
Chagas disease
Trypanosoma cruzi
64
Disease caused by cerebral leptomeningitis in T. brucei
Demyelinating panencephalitis
65
This makes Strongyloides stercoralis bad
Autoinfection and hyperinfection
66
Characteristic of hyperinfection
Strongyloides larva invade colonic submucosa, lymphatics, blood vessels
67
In what muscles does Trichinella spiralis like to encyst?
Striated muscles with rich blood supply (diaphragm, EOMs, deltoid, laryngeal, deltoid, gastrocnemius, intercostals)
68
Found in Trichinella
Nurse cells
69
Causes of lymphatic filariasis
Brugia malayi and Wuchereria bancrofti
70
Intense eosinophilia with hemorrhage and fibrin
Recurrent filarial funiculoepididymitis
71
Found in tropical pulmonary eosinophilia (from filariasis)
Meyers-Kouwenaar bodies
72
Leading cause of preventable blindness in Sub Saharan Africa
Onchocerca volvulus
73
Location of onchocercoma
Subcutaneous nodule
74
Vector of African sleeping sickness (T. brucei)
Tsetse fly
75
Mazzotti reaction
Accentuation of sclerosing keratitis with antifiliarial treatment of Onchocerca
76
Lateral knob of schistosoma
S. japonicum
77
Lateral spine of schistosoma
S. mansoni
78
Terminal spine
S. haematobium
79
Trematode that increases risk of bladder squamous CA
S. haematobium
80
Taenia solium / saginata and Echinococcus granulosus are what kind of worms?
Cestodes
81
Schistosoma is what kind of worm?
Trematode
82
Causative agent of hydatid disease
Echinococcus granulosus
83
Degenerating scolices in Echinococcus
Hydatid sand
84
Taenia solium is found in what kind of meat?
Pork (T. saginata found in beef - think Japanese cows, wagyu)
85
Tapeworms
Cestodes (Ate Ces likes to tape things)
86
Flukes
Trematodes
87
Roundworms
Nematodes (Nema, ang kapatid ni Nemo, is fat and round)