Flashcards in immunity and inflammation Deck (23):
what are the four classifications of hypersensitivity?
specific to cell or tissue and no other sign of cell mediated
IgG and IgM mediated
immune complex mediated
which types is a response to an allergen?
an antigen that causes an allergic reaction; typically foreign proteins from the environment
what are some common allergens
what are characteristics of a type 1 allergic hypersensitivity?
which type of allergic reaction leads to anaphylactic shock?
what are the characteristics of anaphylactic shock?
decreases tissue perfusion
impaired cellular metabolism
what would you give someone to reverse the effects of anaphylactic shock?
all tissue have specific markers or receptors
what are the five steps of type 2 hypersensitivity?
before the five steps there is antibody binding
1-complement mediated lysis
2.phagocytosis by macrophage
4-antibody-dependent cell-mediated cytotoxicity (NK cells)
in type 3, rather than binding to specific antigen (as in type2), on tissues...
effects are mediated by large complexes of antibodies
type 3 causes
not organ specific
type 3 symptoms have little to do with
type 4 recruits
WBC to destroy antigen
what is an example of type 4?
contact dermatitis (poison IV)
is it an allergy?
yes, so then type 1
asthma, hay fever, etc.
are there anybodies?
yes-types 2 or 3
is there binding