Immunity vocab Flashcards

(85 cards)

1
Q

Stratum Corneum

A

Outermost layer of skin

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2
Q

Immunology

A

Encompassses the study of all feautrues of the body’s 2nd and 3rd lines of defense

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3
Q

Self

A

Body cells

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4
Q

Non Self

A

foreign bodies

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5
Q

Markers

A

certain molecules on the surface of cells

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6
Q

Thymus

A

Where T cells mature

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7
Q

Lymph

A

Plasma like liquid carried by the lymphatic circulation

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8
Q

Lymph nodes

A

mall encapsulated bean-shaped orggans stationed along the lymphatic channels and large blood vessels

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9
Q

White Blood Cells

A

Leukocytes

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10
Q

Whole Blood

A

conssts of red blood cells and plasma, what is naturally seen

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11
Q

Hematopoieses

A

the process of forming new red blood cells

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12
Q

WBC

RBC

A

White blood cells

red blood cells

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13
Q

Red blood cells

A

erythrocytes

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14
Q

Platelets

A

thrombocytes

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15
Q

Histiocytes

A

specialized macrophages live in certain tissues and remain there

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16
Q

PAMP

A

Pathogen Associated Molecular Pattern

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17
Q

PAMP definition

A

how cells identify some microbes as foreign

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18
Q

PRR

A

Pathogen Recognition Receptor

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19
Q

PRR definition

A

surface molecules on self cell that recognizes and binds to PAMP

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20
Q

Inflammatory response

A

a reaction to any traumatic event in the tissues

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21
Q

Vasoactive

A

affect the endothelial cells ans smooth muscle cells of blood vessels

affecting the diameter of the blood vessel

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22
Q

Edema

A

local swelling and hardness

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23
Q

Diapedesis

A

migration of WBC out of blood vessels into tissues

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24
Q

Chemotaxis

A

the tendecy for cells to move in response to specific chemical stimuli at the site if injury

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25
FUO
Fever of unknown origin
26
Fever
abnormal elevated body temperature
27
IFN definition
a small protein produced naturally by certain white blood and tissue cells
28
IFN
Interferon
29
1st line defense
any barrier that blocks invasion at the portals of entry by any foreign agents Bind to cell surfaces and induce changes in genetic expression
30
2nd line of defense
system of protective cells and fluids that act when the first line is circumvented
31
IFN Alpha
Stimulate phagocytes
32
IFN Beta
Stimulate Phagocytes
33
IFN Gamma
Product of T Cell | Immune regulator of macrophages and T & B cells
34
Cascade reaction
a sequence of physiological response in which the first substance activates the next substance and so on and so forth
35
Membrane Attack Complex
large ring of proteins that can digest holes in membranes
36
Immunocompetence
the ability of the body to react to with countless foreign substances
37
Antigens
immunogens
38
Immunogens
typically protein or carbs molecules that stimulate a response by the T and B Cells that are highly individual and specific
39
MHC
Major Histocompatability Complex
40
MHC definition
Set of genes that code for human cell markers or receptors
41
HLA
Human Leukocyte Antigen
42
IG
Immunoglobulin
43
Immunoglobulin
Glycoprotein molecue that serves as the antigen receptors f B Cells and antibodies when secreted
44
Antigen Binding Site
end of the forks formed by light and heavy chains
45
Variable Regions
amino acid composition is highly varied from one clone to another on antigen binding sites
46
Constant regions
amino acid content does not vary greatly from one antibody to another on antigen binding sites
47
Clonal Expansion
B or T cell rapidly multiplies
48
Clonal selection
the exact correct B or T cell is activate
49
Clonal Deletion
the destruction of harmful clones that target self
50
Epitope
Molecular fragment that signal that a molecule is foreign
51
Hapton
Foreign material that is too small to illicit a response
52
Alloantigens
cell surface markers and molecules that occur in some hosts of the same species but not other
53
Superantigens
a group of immunogens
54
APC
antigen presenting cell
55
T Cell indepent anitgens
antigens that directly trigger the B Cells to respond without an APC or Hepler T
56
Effector Cells
perform the action of the system
57
NK
Natural Killer Cells
58
Fragments (Ig)
segments on an Ig
59
Fab
the arms that antigen are termed antigen binding fragments
60
Fc
crystallizable fragments, the first segments to become chrystalized in its pure form
61
Natural Immunity
any immunity gained through normal life experiences
62
Artificial immunity
Protection acquired through medical procedures
63
Active Immunity
the body is sensitized and produces antibodies
64
Passive Immunity
the individual recieves antibodies produced in another body
65
Neutralization
prevent proper antigen attachment
66
Agglutinate
causes the antigen to clump
67
antitoxins
neutralize exotoxins
68
Opsonization
Marks a cell for destruction
69
Immunopathology
the study of disease states assoiciated with overactivity or underactivity
70
hyposensitivity disease
immunodeficency, immune functioni is incomplete, depressed, or destroyed
71
Oversensitivity
the body cant distinguuish self from non-self
72
Allergy
exaggerated immune response that is manifested by inflammation
73
allergens
allergy causing antigen
74
inhalant allergens
airborne
75
ingestant allergens
enter by mouth
76
Contactant allergens
enter through the skin
77
Atopy
any chronic local allergy
78
Anaphylaxis
systematic and potentially fatal reaction that involves airway obstruction and ciculatory collapse
79
Cutaneous anaphylaxis
wheal and flare reaction to local injection of allergen
80
Systemic anaphylaxis
sudden respiratory reaction
81
Degranulation
a cellular process that releases antimicrobial cytotoxic or other molecules from secretory vesicles called granules found inside some cells
82
alloantigens
molecules that differ in the same species
83
autoimmunity
hypersensitivity to oneself
84
Primary disease
acquired at birth and stemming from genetic error
85
secondary disease
acquired after birth and caused by natural/artifical agents