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MicroBio Immunity > Lecture Flow Chart > Flashcards

Lecture Flow Chart Flashcards

Cards over the chart made during Lecture (81 cards)

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1
Q

The immune system must

A

recognise friend from foe

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2
Q

Who is foe

A

nonself

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3
Q

Who is friend

A

self

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4
Q

What does the immune system use as its eyes

A

Markers

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5
Q

Examples of Markers

A 
MHC I
MHC II
CD
Ig
TOLL-PAMP
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6
Q

“the name tag””

A

MHC I

MHC II

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7
Q

markers found on all nucleated cells

A

MHC I and MHC II

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8
Q

what does nucleated cells exclude

A

red blood cells

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9
Q

Where are CD markers found

A

T Cells

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10
Q

Where are Ig markers found

A

B Cells

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11
Q

Where are TOLL-PAMP markers found

A

white blood cells

APC and Macrophages

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12
Q

What does the immune system use as words

A

Cytokines

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13
Q

Examples of Cytokins

A

Bradykins
Interleukins
Histamines
prostagladin

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14
Q

Body Compartments

A

RES
ECF
Lymph sys
Vascular sys

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15
Q

Where is the lymph system most condensed

A

the extremites

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16
Q

Why is the lymphatic system more abundant in the hands and feet than the head

A

the extremities are more likely to incur injury

the lymphatic system functions as a drain off

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17
Q

importance of the Caridovasucular system

A

It is how everything gets around the body

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18
Q

RES?

A

Reticuloendothelial System

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19
Q

RES importance?

A

connect lymph and vascular system and the rest of the body

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20
Q

ECF

A

Extracellular Fluid

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21
Q

EFC importance?

A

allows the cells to move between the other 3 compartment

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22
Q

Lymphocytes EX

A

B Cells

T Cells

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23
Q

When do Lymphocytes participate in the immunity process

A

Specific

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24
Q

When do macrophages participate in the immunity process

A

Non-specific

Specific

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25
Macrophages EX
phagocytes
26
When do dendrite participate in the immunity process
non-specific | specific
27
When do neutrophils appears in the immunity process
non-specific
28
When do basophils appears in the immunity process
non-specific
29
When do eosinophils appears in the immunity process
non-specific
30
What is the first line of defense called
Innate
31
What does innate mean
born with the immunity
32
Major types of innate immunity
Physical barrier Chemical barrier Genetic component
33
``` Skin, hair, and nails tears mucus membrane wax voiding Cilia ```
Physical barrier
34
How does genes play a part in innate immunity
the DNA expression is what allows for the body to have them
35
``` Lysozyme salt fatty acids Stomach Acid amylase ```
chemical barrier
36
what is the second line of defense called
Non-specific
37
why is it non-specific
The mechanisms employeed do not target a specific antigen
38
non-specific mechanisms
fever inflammation phagocytosis antimicrobial proteins
39
Which markers recognize antigens
CD | Ig
40
which marker marks pathogens
TOLL-PAMP
41
What does fever do to the body
increases temp increase WBC Decreases pathogen metabolism Decrease available Fe, sugar
42
Antimicrobial proteins
siderphores complement defensins interferons
43
What are the outcomes of complement
Lysis inflammation opsonization
44
What is the process of inflammation
injury vascular reaction edema resolution
45
What is the process of phagocytosis
``` Chemotaxis adhesion engulfment phagolysosome destruction elimination ```
46
what kind of cells release interferons
infected self
47
What kind of reaction is complement
it is a cascade reaction
48
what is a cascade reaction
when one event directly causes subsequent reactions to occur
49
what happens when the 2nd stage was overwhelmed
the 3rd, specific stage sets in
50
antibodies
``` neutralization agglutinate antitoxins opsonization Trigger complement ```
51
Specific process
maturation presentation activation response
52
goal of Vaccination
prodution of memory cells
53
types of immunity
active natural active artifical passive natural passive artifical
54
active natural
sickness
55
active artificial
Vaccination
56
passive natural
breast feeding; from mother
57
passive artificial
antibody therapy
58
Histamine cytokines causes
inflammation
59
Prostaglandin cytokines causes
wheezing
60
Bradykinin cytokines causes
increased mucous production
61
Leukotrienes cytokines triggers
mucous
62
where do the T Cells mature
The thymus
63
where do B Cells mature in the blood
the bone marrow
64
What happens in the presentation stage
APC shows T Cell antigens and T Cell shows B Cells
65
What happens during activation
Proloferation and differentiation
66
what do the lymphocytes differentiate into
B Cells make plasma and memory | T Cells make Helper T and memory
67
How do the lymphocytes respond
B Cells make antibodies | T Cells further differentiate
68
What are antibodies functions
``` complement coat neutralize agglutinate anti-toxin opsonization ```
69
hypersensitivies II
blood incompatibility
70
what happens when blood is incompatable
Self blood can call for antibodies to agglutinate nonself
71
why can mothers blood attack fetus blood
bc of Rh factor incompatibility
72
Hypersensitivies III
antibody complex
73
process of type III
Antibodies clump to attract chompenaters but sometimes they enter the capillary and trigger complement
74
Hypersensitivities IV
coordinates attack against the wrong cells | transplant rejection
75
graph v Host
host accepts tissue and the tissue has its own lymphocytes/immune system and mounts an attack on host
76
Host v Graft
host recognizes the graft as foreign and T Cells attack it
77
Secondary Immundeficency
organic disease, noninfection Chemotherapy Radiation infection
78
Immune Cells
``` dendrites Basophils eosinophils neutrophils lymphocytes macrophages mast cells ```
79
Chompenators
Neutrophils macrophages dendrites
80
APC
B cells dendrites macrophages
81
what happens in type IV conatact dermititis
picks up allogen instead of antigens

MicroBio Immunity (5 decks)

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