Immunology

Question 1

Common variable immunodeficiency

Answer 1

1. Hypogammaglobilinemia(low IgA, IgG, IgM)
2. Low functional Aby testing
3. Clinical manifestations: infection, autoimmune, lymphoproliferation

Question 2

Common variable immunodeficiency

Answer 2

1. Autoimmune
2. Lymphoproliferative
3. Nodular regenerative hyperplasia

Question 3

Nodular regenerative hyperplasia

Answer 3

1. Elevated alkaline phosphates (normal ast and alt)
   2, followed by portal hypertension, jaundice, varices
2. Biopsy required

Question 4

Asplenia required vaccines

Answer 4

1. H. Influenza
2. Pneumococcal
3. Meningococcal

Question 5

Live vaccines:

Answer 5

MMR, intranasal flu, rotavirus, oral polio, smallpox, oral typhoid, yellow fever, BCG