immunology Flashcards

(28 cards)

1
Q

innate involves

A

phagocytes

neutrophils

macrophages

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2
Q

adaptive involves

A

lymphocytes

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3
Q

macrophage engulfs bacterium into a

A

phagosome

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4
Q

the phagosome then fuses with another vesicle called the

A

lysosome

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5
Q

lysosomes are full of chemicals and enzymes that will

A

kill the bacterium

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6
Q

monocytes and macrophages are made in

A

bone marrow (stem cells)

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7
Q

macrophages are found in

A

tissues

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8
Q

macrophages give off chemicals that

A

restrict blood flow away from the site of injury

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9
Q

macrophages produce

A

cytokines

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10
Q

neutrophils are also involved in

A

phagocytosis

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11
Q

eosinophil

A

parasitic infections

allergy and asthma

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12
Q

anaphylactic shock is caused by

A

mast cell degranulation

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13
Q

mast cells protect against

A

parasites

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14
Q

mast cells contain

A

histamine

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15
Q

basophil

A

store histamine

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16
Q

functions of complement

A

induce lysis of microbes MAC

promote phagocytosis

stimulate inflammation

17
Q

cytokinase

A

chemicals used by cells to communicate with other cells

18
Q

maturation of T cells and t cell precursors (macrophages, dendritic cells)

19
Q

spleen: white pulp has 2 zones

A

b cell and t cell

20
Q

spleen: red pulp

A

function is to filter blood

21
Q

t cell are responsible for

A

cell mediated immunity and assisting B cells

CD4 helper and CD8 killer

22
Q

t helper cells

A

cannot kill infected cells or pathogens

23
Q

cytotoxic t cells

A

when exposed to infeted cells they release perforin

form PORES in target cells

induce apoptosis

24
Q

Th2 cells

A

produce different potent cytokines which are regulating mast cells and eosinophil activity

25
only ......... immune responses generate immunological memory
active
26
plasma cells are responsible for .......... production
antibody
27
B cells recognise self AG and
die in the bone marrow by apoptosis
28
antibody structure light chain and heavy chain
binding region and Fc region