immunotherapy

Question 1

What is immunotherapy

Answer 1

Harnessing the power of the immune system to fight disease

Question 2

What is the difference between active and passive immunity after recovery

Answer 2

Passive immunity does not have memory but active immunity leaves the body with memory

Question 3

What are examples of passive immunity

Answer 3

Snake bites where there is a passive infusion of antibody specific to the toxin

Question 4

What is IVIg

Answer 4

Replacement therapy in primary and secondary immunodeficiency disorders

Question 5

What is direct immunotherapy

Answer 5

Antibodies or antibody fragments that detect an antigen on the tumour cell and destroy the target

Question 6

What is indirect immunotherapy

Answer 6

Activating the immune system so that it can seek and find the tumour cells and destroy them

Question 7

What is the first line treatment for non-hodgkin lymphoma

Answer 7

Rituximab

Question 8

What are the 3 E’s

Answer 8

1. Elimination - immune system performs surveillance and elimination of precancer cells
2. Equilibrium - the cancer is established but controlled by the immune system
3. Escape - the cancer mutates and creates strategies to evade the immune system which allows for metastasis

Question 9

Describe CAR T cell therapy

Answer 9

The CAR T cell is engineered to express antigen-targeted receptors for the tumour antigens - leads to better T cell activation against cancers