imprinting 1 better Flashcards

(32 cards)

1
Q

What type of cell do stem cells first differentiate into?

A

Progenitor cells

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2
Q

How are specific genes activated in specific cell types and not in others?

A

Transcription factors

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3
Q

Which type of cells have a haploid genome?

A

Sperm and egg (germ cells)

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4
Q

What type of cell is formed when two haploid cells fuse?

A

Diploid cells

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5
Q

How are haploid cells created from diploid cells?

A

The diploid cells divide by meiosis

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6
Q

Advantages of having two sets of genes?

A

Genetic diversity and a backup set

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7
Q

What did the cloning frogs experiment show?A

A

Each cell has the genetic information necessary to encode for a whole organism

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8
Q

What is the name for a cell containing two male prouclei?

A

Androgenetic

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9
Q

What is the name for a cell containing two female pronuclei?

A

Gynogenetic

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10
Q

What is a parthenogenetic embryo?

A

One oocyte that doubles its haploid genome to become diploid

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11
Q

Where can parthenogenesis occur?

A

Reptiles

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12
Q

What happens if two female pronuclei fuse instead of a male and a female?

A

No extra-embryonic tissue is formed

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13
Q

What happens if two male pronuclei fuse instead of a male and a female?

A

An excessive amount of extra-embryonic tissue and no embryonic tissue

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14
Q

What can maternal genes not form?

A

A placenta

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15
Q

What can paternal genes not form?

A

An embryo

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16
Q

What are hydatidiform moles?

A

Growths that occur in the ovum that occur instead of pregnancy

17
Q

What causes hydatidiform moles?

A

Empty ovum (all genome is polar bodies and after fertilisation there is only a male contribution) or the ovum is fertilised by two sperm

18
Q

What causes prader willi/angelman syndrome?

A

A deletion in chromosome 15

19
Q

What condition comes about as a result of a deletion in the paternal chromosome 15?

A

Prader willi syndrome

20
Q

What condition comes about as a result of a deletion in the maternal chromosome 15?

A

Angelman syndrome

21
Q

Main symptoms of prader willi syndrome?

A

Obesity, metabolic issues

22
Q

Main symptoms of angelman syndrome?

A

Growth retardation, underweight

23
Q

What was observed after knocking a section of chromosome 15 out in male mice?

A

Male and female offspring had prader willi symptoms

24
Q

What was observed after knocking a section of chromosome 15 out in female mice?

A

offspring were carriers

25
What are primordial gem cells?
Cells in the embryo that will become that organisms future gametes
26
When are imprints established?
After the primordial germ cells have migrated to the genital ridge
27
What are imprinting marks?
Methylation marks put on genes in primordial germ cells to help them differentiate into egg cells or sperm cells
28
What is different from imprinted genes to normal methylation on genes?
The imprint remains on some genes in the egg and sperm after fertilisation
29
What happens to imprinted genes during the development of the embryo?
They are read differently during the development of the embryo
30
In which cells in the embryo are imprinted marks erased?
The primordial germ cells (still have parents imprinted marks on them)
31
Why are imprinted marks on the PGCs erased?
So that when they get to the genital ridge they can have that embryos imprint marks added
32