Incorrect MCQ - Week of 11/25 Flashcards
What is Dourine disease?
How is it transmitted?
What is the etiologic agent?
What are the clinical signs?
Is this disease commonly found in the U.S?
This disease is similar to what other disease process of horses?
Dourine disease is a chronic venereal disease of horses.
Transmitted during sexual intercourse.
Etiologic agent is Trypanosoma equiperdum.
Clinical signs include mucoid vaginal discharge (containing trypanosomes) and genital edema in mares and progresses to gross edema of the genitalia, “silver dollar” dermal plaques, emaciation, progressive paralysis.
This disease is not commonly found in the U.S. It is reportable!!
This disease is similar to Contagious Equine Metritis. Caused by Taylorella equigenitalis. Think of mucopurulent vaginal discharge & endometritis in a horse recently imported from Europe or Japan. This disease is reportable!!!
What dog breeds are prediposed to developing dilated cardiomyopathy?
List the etiologies of DCM.
List the diagnostic and tx options for DCM.
Prognosis
Great Danes
Doberman Pinschers
Irish Wolfounds
Standard Poodles
Boxers
Cocker Spaniels
Etiologies:
1. Taurine deficiency
2. Carnitine responsive - boxers
3. Chagas disease
4. Parvovirus infection (in utero) - rare b/c of vaccination
5. Adriamycin/Doxorubicin (cumulative doses)
Dx:
1. Radiographs = generalized cardiomegaly, dilated pulmonary vessels, +/- perihilar infiltrate in compensated disease
2. ECG: ventricular ectopic beats commonly seen
3. Echo: LA and LV dilation (left auricular bulge), mitral valve regurg, +/- RA and RV dilation
Tx:
1. Antiarrthymics: Sotalol, mexilitene
2. ACE Inhibitors: Enalapril (Inhibits conversion of angiotensin I into angiotensin II –> lowers BP)
3. Positive ionotrope/Inodilator: Pimobendan (increases cardiac contractility and promotes vasodilation)
4. Loop diuretic: Furosemide (for CHF cases)
Prognosis is fair. Dogs can live for several years. If started before onset of CHF, Pimobendan can extend life expectancy by 1 yr but then prognosis after that is poor.
Dobermans have two genetic mutations that can lead to the development of DCM - name them. What is the likelihood of developing DCM if a patient has both genetic mutations?
PDK4, DCM2
Dogs with both genetic mutations are 30x more likely to develop DCM than a normal dog.
Define insensible fluids. What is the normal volume loss for insensible fluids in a dog for a 24-hr time period?
Insensible fluids are fluids the animals loses that are hard to measure, such as breathing.
20 ml/kg/day
What are the clinical signs of small intestinal incarceration or strangulation in horses?
How is it diagnosed? Treated?
SI incarceration can occur through?
C/S: Progressively painful, copious nasogastric reflux, deteriorating metabolic status
Dx:
1. Rectal exam - multiple loops of distended small intestine
2. Rectal US - same as above
3. Place NG tube - copious NG reflux (more than 2L)
Tx: Sx +/- resection
SI incarceration can occur through the epiploic foramen, mesenteric rents, inguinal orifice, umbilical orifice
Define Evans syndrome.
What dog breed is predisposed to this condition?
Evans syndrome is IMHA + IMT
Cocker spaniels are prediposed.
Pseudocowpox leave what characteristic lesion?
Pseudocowpox heal from the center and leave a characteristic horseshoe or ring of scabs.
This disease is zoonotic! Milkers will have lesions on their hands.
Prolonged tx for EPM with antifolate AB like sulfadiazine or sulfamethoxazole may cause?
Anemia
Monitor CBC
What is the meningeal worm of white-tailed deer? What does it cause?
Paralaphostrongylus tenuis (P. tenuis) causes traumatic and inflammatory myeloencephalomeningitis in cervids, goats, and sheep and less often can infect cattle and camelids. Pass through host CNS as part of their lifecycle.
What AB should be avoided when treating cases of botulism and why?
Gentamicin, an aminoglycoside AB, should be avoided due to its association with the adverse effect of neuromuscular blockade. Other adverse effects of aminoglycosides include nephrotoxicity and ototoxicity.
Necroticizing meningoencephalitis is most commonly seen in what dog breeds of what age group?
What are the clinical signs? Dx? Tx?
Prognosis
Pugs < 5 yo (usually around 18 mo old), Maltese, Yorkie, Chihuahua, French bulldogs
Clinical signs include forebrain, brainstem, or meningitis neurological signs.
Dx: MRI, CSF tap
Tx:
1. Anti-seizure medications
2. Immunosuppressants: corticosteroids +/- cyclosporine, mycophenolate, cytarabine
Prognosis is fair to guarded; 1-2 yrs
What types of flies are these? What disease do they carry?
What are the C/S, dx, and tx? Prevention?
These are horn flies and they carry Stephanofilaria stilesi, the causative agent of stephanofilariasis.
C/S: plaque-like dermatitis along the ventral midline of cattle.
Dx: microfilaria on deep skin scraping.
Tx: Incidental finding - no tx needed.
Prevention: Dust bags, feed-through insect growth regulators or insecticides, insecticide impregnated ear tags, or pour-on insecticides.
What are the clinical signs of pericardial effusion in a dog? List the etiologies, diagnostics, and tx
C/S: Exercise intolerance, tachycardia, tachypnea, muffled heart sounds, abdominal distension, pale mm, pulsus paradoxocus
Dx:
1. Radiographs - round, globoid cardiac silhouette; dilated caudal vena cava, ascites
2. ECG - tachycardia, electrical alterans
3. Echocardiogram - fluid filled pericardium, failing right heart, possible mass
Tx:
1. Pericardiocentesis, possible pericardectomy if recurrent effusions occurring.
2. If right auricular hemangiosarcoma - possible surgical resection
3. If lymphoma, chemodectoma, mesothelioma, or RA HSA = chemotherapy
Primiparous blood type B queens can have anti-A antibodies with or without prior exposure?
WITHOUT prior exposure
Type A queens can have anti-B antibodies but these are weaker than the antibodies seen in type B queens
Why do dogs with iatrogenic hyperadrenocorticism have little to no response to ACTH stim tests?
Chronic steroid use –> negative feedback on adrenals –> renal atrophy –> little to no response to ACTH stim test
What volume of daily water consumption is consistent with polydipsia in a dog?
Over 100 ml/kg/d
How long is estrus in gilts compared to multiparous sows?
Estrus is shorter in gilts compared to multiparous sows
Describe cryptosporidiosis in an adult corn snake.
Cryptosporidiosis affect the gastric mucosa causing decreased segmented motility and significant thickening of the gastric rugae.
C/S: Postprandial regurgitation, weight loss, chronic debilitation.
Dx: Contrast radiographs, endoscopy, acid-fast feces staining, etc.
Tx: Hyperimmune bovine colostrum has been consistently effective + aggressive supportive care. Euthanasia is reasonable. NOT ZOONOTIC
What bony disorder an develop secondary to Spirocerca lupi infection?
Hypertrophic osteopathy
- Look for lesions at the distal aspect of all four limbs.
Spirocerca lupi affects the esophagus, aorta, and thoracic vertebrae
The use of compounded medication is an example of?
Extra-label drug use
How many vertebrae do dogs have? Cats?
Dogs - 54 vertebrae (7 cervical, 13 thoracic, 7 lumbar, 3 sacral, 20-23 caudal vertebrae in tail)
Cats - 30 (7 cervical, 13 thoracic, 7 lumbar, 3 sacral, 18-23 caudal vertebrae in tail)
Foals whose dams are fed what supplements can be born with a hyperplastic goiter?
Kelp, rape, cabbage, soybeans, kale, turnips
Loss of patellar reflex and inability to bear weight on the hind limbs means there is a lesion at what spinal vertebrae?
L4-L6
When see loss of patellar reflex thing femoral nerve!
Intact withdrawal reflex means what nerve is intact? What spinal vertebrae is this nerve located at?
Sciatic nerve, L7-S1