Individual BDZ agents Flashcards Preview

Cology 2 Exam 1 > Individual BDZ agents > Flashcards

Flashcards in Individual BDZ agents Deck (15):
1

Zolpidem

Sleep disorders
Binds alpha1 ONLY

2

Zaleplon

Binds alpha-1 only, sedation

3

Eszopiclone

Binds alpha-1 only, sedation

4

Indiplon

Binds alpha-1 only, sedation

5

Clobazam

Binds alpha 2 subunits only
Used for Lennox-gastaut syndrome (seizures in children)
Less sedative/cognitive effects

6

Bretazenil

Full agonist for alpha 5
Antagonist at alpha 1
Anxiolytic and anticonvulsant, very little sedative effects

7

Imidazenil

Full agonist for alpha 5
Antagonist at alpha 1
Anxiolytic and anticonvulsant, very little sedative effects

8

Loreclezole

Selective for receptors containing beta-2 subunit
Can also stimulate GABA-A receptor in the absence of GABA

9

Buspirone

5-HT1A partial agonists, anxiolytic (takes weeks to work)

10

Gepirone

5-HT1A partial agonist, anxiolytic (takes weeks to work)

11

Ondansetron

5-HT3 antagonist

12

Clonidine

Decreases norepinephrine release via autoreceptor activation

13

Oxytocin

Decreases ethanol withdrawal-induced anxiety

14

Nitrazepam

Selective anticonvulsant

15

Nordazepam

Selective anticonvulsant